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Vestibular-evoked myogenic potentials and subjective visual vertical testing in patients with vitamin D deficiency/insufficiency

  • Otology
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Abstract

Otolith function in subjects with vitamin D deficiency/insufficiency is investigated through vestibular-evoked myogenic potentials (VEMP) and subjective visual vertical (SVV) testing. The study group included 62 patients with vitamin D deficiency/insufficiency (30 females, 32 males), with age range 24–56 years (40.6 ± 9.1). The control group included 44 healthy volunteers of similar age and gender distribution. The entire study group had: (1) serum level of 25-hydroxyvitamin D <30 ng/ml; (2) normal bone mineral density as indicated by dual-energy X-ray absorptiometry with T-score >−1; (3) normal middle ear function; (4) Age is ≤60 years. All subjects enrolled in the current study underwent audiovestibular evaluation consisting of pure-tone audiometry, immittancemetry, cervical VEMP (cVEMP), ocular VEMP (oVEMP), and SSV. The entire control group had normal cVEMP, two subjects had abnormal oVEMP. Thirty-three subjects (53 %) in the study group had abnormal oVEMP and 31 subjects (50 %) had abnormal cVEMP. Forty-one (66 %) had abnormal VEMP when abnormal VEMP was considered as either abnormal oVEMP or cVEMP. The entire control and study groups had normal SSV test results. Vitamin D deficiency may be associated with development of otolith dysfunction affecting both the utricle and saccule. This was suggested by the high prevalence of abnormal ocular vestibular-evoked myogenic potentials (oVEMP) and cervical vestibular-evoked myogenic potentials (cVEMP) in the study group.

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Authors and Affiliations

  1. Audiology Unit, ENT Department, Menoufiya University, Shibin Al Kawm, Al Minufiyah, Egypt

    Hossam Sanyelbhaa

  2. Internal Medicine Department, Suez Canal University, Ismaileya, Egypt

    Ahmed Sanyelbhaa

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  1. Hossam Sanyelbhaa
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  2. Ahmed Sanyelbhaa
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Correspondence to Hossam Sanyelbhaa.

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Sanyelbhaa, H., Sanyelbhaa, A. Vestibular-evoked myogenic potentials and subjective visual vertical testing in patients with vitamin D deficiency/insufficiency. Eur Arch Otorhinolaryngol 272, 3233–3239 (2015). https://doi.org/10.1007/s00405-014-3395-6

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  • DOI: https://doi.org/10.1007/s00405-014-3395-6

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