Prognostic effect of hyperbaric oxygen therapy starting time for sudden sensorineural hearing loss

European Archives of Oto-Rhino-Laryngology volume 272, pages23–28(2015)Cite this article

Abstract

Sudden sensorineural hearing loss is one of the otological emergencies whose pathogenesis is uncertain and associated with total or partial loss of hearing function. The aim of this study was to investigate whether the hyperbaric oxygen therapy starting time affects the management of sudden sensorineural hearing loss. Fifty-nine patients with sudden sensorineural hearing loss admitted to our clinic between 2008 and 2012 were retrospectively included in this study. All patients received hyperbaric oxygen therapy. In addition, each patient received intravenous piracetam and 37 patients received steroid therapy. Hyperbaric oxygen therapy was initiated between 1 and 7 days with 20 patients determined as Group A, between 8 and 14 days with 25 patients determined as Group B and between 15 and 28 days with 14 patients determined as Group C. Hearing gains of these three groups were statistically evaluated. Each of them showed statistically significant improvement. Lowest hearing gain was observed in Group C and the gain of this group was statistically less than the other two groups. There was no significant difference between the hearing gains of the Group A and Group B. Starting hyperbaric oxygen therapy in patients with sudden sensorineural hearing loss within the first 14 days has positive effect on the prognosis of the disease.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

US$ 39.95

Tax calculation will be finalised during checkout.

References

  1. 1.

    Arts HA (1998) Sudden sensorineural hearing loss. In: Cummings CW, Fredericson JM, Harker LA et al (eds) Otololaryngology head and neck surgery. Mosby Year Book, London, pp 2923–2933

    Google Scholar 

  2. 2.

    Akyıldız N (2002) Ani sağırlıklar. In: Akyıldız N (ed) Kulak Hastalıkları ve Mikrocerrahisi, 2nd edn. Bilimsel TıpYayınevi, Ankara, pp 35–43

    Google Scholar 

  3. 3.

    Wilson WR, Byl FM, Laird N (1980) The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 106:772–776

    CAS  PubMed  Article  Google Scholar 

  4. 4.

    Mattox DE, Simmons FB (1977) Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol 86:463–480

    CAS  PubMed  Article  Google Scholar 

  5. 5.

    Hughes GB, Freedman MA, Haberkamp TJ, Guay ME (1996) Sudden sensorineural hearing loss. Otolaryngol Clin N Am 29:393–405

    CAS  Google Scholar 

  6. 6.

    Lazarini PR, Camargo AC (2006) Idiopathic sudden sensorineural hearing loss: etiopathogenic aspects. Braz J Otorhinolaryngol 72:554–561

    PubMed  Google Scholar 

  7. 7.

    Dundar K, Gumus T, Ay H et al (2007) Effectiveness of hyperbaric oxygen on sudden sensorineural hearing loss: prospective clinical research. J Otolaryngol 36:32–37

    PubMed  Article  Google Scholar 

  8. 8.

    Taylor DM, Lippmann J, Smith D (2006) The absence of hearing loss in otologically asymptomatic recreational scuba divers. Undersea Hyperb Med 33:135–141

    PubMed  Google Scholar 

  9. 9.

    Inanli S, Tutkun A, Batman C (2002) Ani işitme kayıplı olgularımızda tedavi ve prognozun retrospektif analizi. Türk Otolaringoloji Arşivi 40:196–200

    Google Scholar 

  10. 10.

    Linssen O, Schultz-Coulon HJ (1997) Prognostic criteria in sudden deafness. HNO 45:22–29

    CAS  PubMed  Article  Google Scholar 

  11. 11.

    Byl FM Jr (1984) Sudden hearing loss: eight years’ experience and suggested prognostic table. Laryngoscope 94:647–661

    PubMed  Article  Google Scholar 

  12. 12.

    Muzzi E, Zennaro B, Visentin R et al (2010) Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: review of rationale and preliminary report. J Laryngol Otol 124:e2

    CAS  PubMed  Article  Google Scholar 

  13. 13.

    Korpinar S, Alkan Z, Yigit O et al (2011) Factors influencing the outcome of idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy. Eur Arch Otorhinolaryngol 268:41–47

    PubMed  Article  Google Scholar 

  14. 14.

    Holy R, Navara M, Dosel P et al (2011) Hyperbaric oxygen therapy in idiopathic sudden sensorineural hearing loss (ISSNHL) in association with combined treatment. Undersea Hyperb Med 38:137–142

    CAS  PubMed  Google Scholar 

  15. 15.

    Nosrati-Zarenoe R, Arlinger S, Hultcrantz E (2007) Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Otolaryngol 127:1168–1175

    PubMed  Article  Google Scholar 

  16. 16.

    Liu SC, Kang BH, Lee JC et al (2011) Comparison of therapeutic results in sudden sensorineural hearing loss with/without additional hyperbaric oxygen therapy: a retrospective review of 465 audiologically controlled cases. Clin Otolaryngol 36:121–128

    PubMed  Article  Google Scholar 

  17. 17.

    Shikowitz MJ (1991) Sudden sensorineural hearing loss. Med Clin North Am 75:1239–1250

    CAS  PubMed  Google Scholar 

  18. 18.

    Oh JH, Park K, Lee SJ et al (2007) Bilateral versus unilateral sudden sensorineural hearing loss. Otolaryngol Head Neck Surg 136:87–91

    PubMed  Article  Google Scholar 

  19. 19.

    Cekin E, Cincik H, Ulubil SA, Gungor A (2009) Effectiveness of hyperbaric oxygen therapy in management of sudden hearing loss. J Laryngol Otol 123:609–612

    CAS  PubMed  Article  Google Scholar 

  20. 20.

    Gordin A, Goldenberg D, Golz A et al (2002) Magnesium: a new therapy for idiopathic sudden sensorineural hearing loss. Otol Neurotol 23:447–451

    PubMed  Article  Google Scholar 

  21. 21.

    Stokroos RJ, Albers FW, Tenvergert EM (1998) Antiviral treatment of idiopathic sudden sensorineural hearing loss: a prospective, randomized, double-blind clinical trial. Acta Otolaryngol 118:488–495

    CAS  PubMed  Article  Google Scholar 

  22. 22.

    Inci E, Erişir F, Ada M, Oztürk O, Güçlü E, Oktem F, Toprak M (2002) Hyperbaric oxygen treatment in sudden hearing loss after unsuccessful medical treatment. Kulak Burun Bogaz Ihtis Derg 9(5):337–341

    PubMed  Google Scholar 

  23. 23.

    García-Callejo FJ, Marco-Algarra J, Pla-Gil I, Monzó-Gandía R, Juantegui-Azpilicueta M, Martínez-Beneyto P (2012) Pathologic erythrocyte deformability in patients with sudden sensorineural hearing loss. Acta Otorrinolaringol Esp 63(4):249–257

    PubMed  Article  Google Scholar 

  24. 24.

    Moskowitz D, Lee KJ, Smith HW (1984) Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope 94:664–666

    CAS  PubMed  Article  Google Scholar 

  25. 25.

    Westerlaken BO, de Kleine E, van der Laan B, Albers F (2007) The treatment of idiopathic sudden sensorineural hearing loss using pulse therapy: a prospective, randomized, double-blind clinical trial. Laryngoscope 117:684–690

    PubMed  Article  Google Scholar 

  26. 26.

    Cvorovic L, Jovanovic MB, Milutinovic Z et al (2013) Randomized prospective trial of hyperbaric oxygen therapy and intratympanic steroid injection as salvage treatment of sudden sensorineural hearing loss. Otol Neurotol 34:1021–1026

    PubMed  Article  Google Scholar 

  27. 27.

    Yang CH, Wu RW, Hwang CF (2013) Comparison of intratympanic steroid injection, hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss. Otol Neurotol 34:1411–1416

    PubMed  Article  Google Scholar 

  28. 28.

    Imsuwansri T, Poonsap P, Snidvongs K (2012) Hyperbaric oxygen therapy for sudden sensorineural hearing loss after failure from oral and intratympanic corticosteroid. Clin Exp Otorhinolaryngol 5(Suppl 1):S99–S102

    PubMed Central  PubMed  Article  Google Scholar 

  29. 29.

    Alimoglu Y, Inci E, Edizer DT et al (2011) Efficacy comparison of oral steroid, intratympanic steroid, hyperbaric oxygen and oral steroid + hyperbaric oxygen treatments in idiopathic sudden sensorineural hearing loss cases. Eur Arch Otorhinolaryngol 268:1735–1741

    PubMed  Article  Google Scholar 

  30. 30.

    Aslan I, Oysu C, Veyseller B, Baserer N (2002) Does the addition of hyperbaric oxygen therapy to the conventional treatment modalities influence the outcome of sudden deafness? Otolaryngol Head Neck Surg 126(2):121–126

    PubMed  Article  Google Scholar 

  31. 31.

    Topuz E, Yigit O, Cinar U, Seven H (2004) Should hyperbaric oxygen be added to treatment in idiopathic sudden sensorineural hearing loss? Eur Arch Otorhinolaryngol 261(7):393–396

    PubMed  Article  Google Scholar 

  32. 32.

    Roding B, Groeneveld PH, Boerema I (1972) Ten years of experience in the treatment of gas gangrene with hyperbaric oxygen. Surg Gynecol Obstet 134:579–585

    CAS  PubMed  Google Scholar 

  33. 33.

    Eloff SJ, Brummelkamp WH, Boerema I (1963) A case of “Ergot Foot” treated with hyperbaric oxygen drenching. J Cardiovasc Surg (Torino) 4:747–751

    CAS  Google Scholar 

  34. 34.

    Pilgramm M, Schumann K (1985) Hyperbaric oxygen therapy for acute acoustic trauma. Arch Otorhinolaryngol 241:247–257

    CAS  PubMed  Article  Google Scholar 

  35. 35.

    Lamm H, Lamm K, Zimmermann W (1982) The effects of hyperbaric oxygen on experimental noise damage to the ears. Arch Otorhinolaryngol 236:237–244

    CAS  PubMed  Article  Google Scholar 

  36. 36.

    Giebfried JW, Lawson W, Biller HF (1986) Complications of hyperbaric oxygen in the treatment of head and neck disease. Otolaryngol Head Neck Surg 94:508–512

    CAS  PubMed  Google Scholar 

  37. 37.

    Densert B, Densert O (1982) Overpressure in treatment of Meniere’s disease. Laryngoscope 92:1285–1292

    CAS  PubMed  Article  Google Scholar 

  38. 38.

    Meller R, Rostain JC, Luciano M et al (2003) Does repeated hyperbaric exposure to 4 atmosphere absolute cause hearing impairment? Study in Guinea pigs and clinical incidences. Otol Neurotol 24:723–727

    PubMed  Article  Google Scholar 

  39. 39.

    Beckman DL, Crittenden DJ, Overton DH 3rd, Blumenthal SJ (1982) Influence of blood glucose on convulsive seizures from hyperbaric oxygen. Life Sci 31:45–49

    CAS  PubMed  Article  Google Scholar 

  40. 40.

    Murphy-Lavoie H, Piper S, Moon RE, Legros T (2012) Hyperbaric oxygen therapy for idiopathic sudden sensorineural hearing loss. Undersea Hyperb Med 39:777–792

    CAS  PubMed  Google Scholar 

  41. 41.

    Nakashima T, Fukuta S, Yanagita N (1998) Hyperbaric oxygen therapy for sudden deafness. Adv Otorhinolaryngol 54:100–109

    CAS  PubMed  Google Scholar 

Download references

Author information

Affiliations

  1. Department of Otorhinolaryngology, Kars State Hospital, Örnek Mah, 36200, Merkez, Kars, Turkey

    Erol Yıldırım

  2. Department of Otorhinolaryngology, Numune Education and Research Hospital, Ülkü Mah, Talatpaşa Bulv. No: 5, Altındağ, Ankara, Turkey

    K. Murat Özcan, Mehmet Palalı, Mehmet Ali Cetin, Serdar Ensari & Hüseyin Dere

Authors
  1. Erol Yıldırım
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. Murat Özcan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mehmet Palalı
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mehmet Ali Cetin
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Serdar Ensari
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hüseyin Dere
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Erol Yıldırım.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Yıldırım, E., Murat Özcan, K., Palalı, M. et al. Prognostic effect of hyperbaric oxygen therapy starting time for sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 272, 23–28 (2015). https://doi.org/10.1007/s00405-013-2829-x

Download citation

Keywords

  • Sudden sensorineural hearing loss
  • Hyperbaric oxygen therapy
  • Prognosis