Involvement of peripheral vestibular nerve in individuals with auditory neuropathy
- 363 Downloads
The vestibulocochlear nerve is a sensory nerve that serves the organs of hearing and equilibrium. Neuropathies of the nerve, particularly auditory neuropathy may be caused by primary demyelination or by axonal diseases. In disorders affecting the cochlear nerve, it is probable that the vestibular nerve is involved as well. There are isolated reports of the involvement of the inferior vestibular nerve (using vestibular-evoked myogenic potentials) in individuals with AN. However, there is a dearth of information on the involvement of the superior vestibular nerve and other functions such as optokinetic, saccade and vestibulo-occular reflex. A total of three subjects diagnosed as having auditory neuropathy, underwent an extensive vestibular assessment consisting of clinical tests of stability (Romberg, Fukuda stepping test), administration of dizziness questionnaire developed by Maryland hearing and balance centre, cervical vestibular-evoked myogenic potentials and a standard electronystagmography test battery. In the present study, the entire subject population assessed showed hypofunctional caloric responses and absent VEMPs. Two out of the three subjects were asymptomatic of vestibular dysfunction. On the clinical tests of stability, two subjects showed deviations to the right, while one subject performed normally. Thus, the present study indicates a possible involvement of peripheral vestibular nerve involvement in individuals with auditory neuropathy.
KeywordsAuditory neuropathy Vestibular-evoked myogenic potentials Electronystagmography Vestibular neuropathy
- 4.Berlin CI, Hood LJ, Goforth-Barter L, Bordelon J (1999) Clinical application of auditory efferent studies. In: Berlin CI (ed) The efferent auditory system: basic sciences and clinical applications. Singular-Thompson Learning, San Diego, pp 105–124Google Scholar
- 7.Fujikawa S, Starr A (2000) Vestibular neuropathy accompanying auditory and peripheral neuropathies. Arch Otolaryngol Head Neck Surg 126:1463–1456Google Scholar
- 9.Kumar K, Sinha SK, Singh NK, Bharti AK, Barman A (2007) Vestibular evoked myogenic potential as a tool to identify vestibular involvement in auditory neuropathy. Asia P J Sp Lang Hear 10(3):181–187Google Scholar
- 15.Quarles RH, Macklin WB, Morell P (2006) Myelin formation, structure and biochemistry. In: Siegel G, Albers RW, Brady S, Price D (eds) Basic neurochemistry, 7th edn. Elsevier Academic Press, London, pp 51–72Google Scholar