Skip to main content

Supracricoid partial laryngectomy cricohyoidoepiglottopexy (SCPL-CHEP) versus vertical partial laryngectomy for the treatment of glottic carcinoma

European Archives of Oto-Rhino-Laryngology volume 270, pages 1027–1034 (2013)Cite this article

Abstract

The study aimed to compare the survival rate and functional outcome of supracricoid partial laryngectomy cricohyoidoepiglottopexy (SCPL-CHEP) and vertical partial laryngectomy (VPL) in the treatment of glottic carcinoma. Thirty-nine patients underwent SCPL-CHEP and 45 patients underwent VPL between 2002 and 2007. Post-operative clinical staging were performed according to the UICC staging criteria (2002). The primary endpoints were survival time and recurrence rate. The secondary endpoints were the laryngeal functions including pronunciation, swallowing, and respiration. Overall, the estimated mean survival time was 75.6 months. There was no significant difference in survival times between the two groups (P = 0.496). The SCPL-CHEP group had a significantly lower post-operative local recurrence rate than VPL group (2.6 vs. 17.8 %, P = 0.033). Significantly longer nasogastric tube removal (22 vs. 14 days, P < 0.001) and tracheostomy decannulation (38.5 vs. 15 days, P < 0.001) times in SCPL-CHEP group was observed with the VPL group, respectively. Significantly higher aspiration rates were observed at 3, 6, and 12 months in the SCPL-CHEP group compared with the VPL group (P < 0.001, P < 0.001, P < 0.05, respectively). Although the survival rate was not significantly different between the two groups, the local regional control rate and organ preservation in the supracricoid partial laryngectomy cricohyoidoepiglottopexy group was better than those observed in the vertical partial laryngectomy group.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

43,34 €

Price includes VAT (Finland)
Tax calculation will be finalised during checkout.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61(2):69–90

    PubMed  Article  Google Scholar 

  2. World Cancer Research Fund International. General world cancer statistics (2008) http://www.wcrf.org/cancer_statistics/world_cancer_statistics.php. Accessed July 2 2012

  3. Jaseviciene L, Gurevicius R, Obelenis V, Cicenas S, Juozulynas A (2004) Trends in laryngeal cancer incidence in Lithuania: a future perspective. Int J Occup Med Environ Health 17(4):473–477

    PubMed  Google Scholar 

  4. Liu X, Chen Z, Yu J, Xia J, Zhou X (2009) MicroRNA profiling and head and neck cancer. Comp Funct Genomics 2009:837514

    Article  Google Scholar 

  5. Xie L, Tian YQ, ZHAO SP, Liu LW, Qiu YZ, Xiao JY (2009) Prognostic multivariate analysis of laryngeal squamous cell carcinoma in 335 patients with surgical treatment. Chin J Otorhinolaryngol Skull Base Surg 15(6):426–431

    Google Scholar 

  6. Lefebvre JL (2006) Laryngeal preservation in head and neck cancer: multidisciplinary approach. Lancet Oncol 7(9):747–755

    PubMed  Article  Google Scholar 

  7. Pfister DG, Ridge JA (2006) Induction chemotherapy for larynx preservation: patient selection or therapeutic effect? J Clin Oncol 24(4):540–543

    PubMed  Article  Google Scholar 

  8. Majer EH, Rieder W (1959) Technique de laryngectomie permettant de conserver la permeabilite respiratoire : la crico-hyoidopexie. Ann Otolaryngol Chir Cervicofac 76:677–683

    CAS  Google Scholar 

  9. Laccourreye H, Laccourreye O, Weinstein G, Menard M, Brasnu D (1990) Supracricoid laryngectomy with cricohyoidoepiglottopexy: a partial laryngeal procedure for glottic carcinoma. Ann Otol Rhinol Laryngol 99(6 Pt 1):421–426

    PubMed  CAS  Google Scholar 

  10. Brasnu DF (2003) Supracricoid partial laryngectomy with cricohyoidopexy in the management of laryngeal carcinoma. World J Surg 27(7):817–823

    PubMed  Article  Google Scholar 

  11. Sanchez-Cuadrado I, Castro A, Bernaldez R, Del Palacio A, Gavilan J (2011) Oncologic outcomes after supracricoid partial laryngectomy. Otolaryngol Head Neck Surg 144(6):910–914

    PubMed  Article  Google Scholar 

  12. Bron L, Pasche P, Brossard E, Monnier P, Schweizer V (2002) Functional analysis after supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Laryngoscope 112(7 Pt 1):1289–1293

    PubMed  Article  Google Scholar 

  13. Laccourreye H, Laccourreye O, Weinstein G, Menard M, Brasnu D (1990) Supracricoid laryngectomy with cricohyoidopexy: a partial laryngeal procedure for selected supraglottic and transglottic carcinomas. Laryngoscope 100(7):735–741

    PubMed  Article  CAS  Google Scholar 

  14. Marshak G, Brenner B, Shvero J et al (1999) Prognostic factors for local control of early glottic cancer: the Rabin Medical Center retrospective study on 207 patients. Int J Radiat Oncol Biol Phys 43(5):1009–1013

    PubMed  Article  CAS  Google Scholar 

  15. Laccourreye O, Muscatello L, Laccourreye L, Naudo P, Brasnu D, Weinstein G (1997) Supracricoid partial laryngectomy with cricohyoidoepiglottopexy for “early” glottic carcinoma classified as T1–T2N0 invading the anterior commissure. Am J Otolaryngol 18(6):385–390

    PubMed  Article  CAS  Google Scholar 

  16. Laccourreye O, Salzer SJ, Brasnu D, Shen W, Laccourreye H, Weinstein GS (1996) Glottic carcinoma with a fixed true vocal cord: outcomes after neoadjuvant chemotherapy and supracricoid partial laryngectomy with cricohyoidoepiglottopexy. Otolaryngol Head Neck Surg 114(3):400–406

    PubMed  Article  CAS  Google Scholar 

  17. Laccourreye O, Weinstein G, Brasnu D et al (1994) A clinical trial of continuous cisplatin-fluorouracil induction chemotherapy and supracricoid partial laryngectomy for glottic carcinoma classified as T2. Cancer 74(10):2781–2790

    PubMed  Article  CAS  Google Scholar 

  18. Gallo A, Manciocco V, Simonelli M, Pagliuca G, D’Arcangelo E, de Vincentiis M (2005) Supracricoid partial laryngectomy in the treatment of laryngeal cancer: univariate and multivariate analysis of prognostic factors. Arch Otolaryngol Head Neck Surg 131(7):620–625

    PubMed  Article  Google Scholar 

  19. Lin RY, Chen JF, Guo ZQ, Peng JH, Zhou J, Fang WQ (2010) Comparing extended vertical partial laryngectomy and cricohyoidoepiglottopexy in the treatment of laryngeal carcinoma. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 45(4):305–309

    PubMed  Google Scholar 

  20. de Vincentiis M, Minni A, Gallo A, Di Nardo A (1998) Supracricoid partial laryngectomies: oncologic and functional results. Head Neck 20(6):504–509

    PubMed  Article  Google Scholar 

  21. Pellini R, Manciocco V, Spriano G (2006) Functional outcome of supracricoid partial laryngectomy with cricohyoidopexy: radiation failure vs previously untreated cases. Arch Otolaryngol Head Neck Surg 132(11):1221–1225

    PubMed  Article  Google Scholar 

  22. Yuceturk AV, Tarhan S, Gunhan K, Pabuscu Y (2005) Videofluoroscopic evaluation of the swallowing function after supracricoid laryngectomy. Eur Arch Otorhinolaryngol 262(3):198–203

    PubMed  Article  Google Scholar 

  23. Zhou L (2005) Supracricoid partial laryngectomy in the treatment of supraglottic laryngeal carcinoma. Chin Arch Otolaryngol Head Neck Surg 12(4):205–207

    Google Scholar 

  24. Pan Z, Guo X, Ji W (2000) Study of mechanisms of lightening aspiration and increasing decannulation rate in anastomosis of cricoid cartilage and base of tongue (epiglottis). Zhonghua Er Bi Yan Hou Ke Za Zhi 35(6):475–478

    PubMed  CAS  Google Scholar 

  25. Laccourreye O, Brasnu D, Perie S, Muscatello L, Menard M, Weinstein G (1998) Supracricoid partial laryngectomies in the elderly: mortality, complications, and functional outcome. Laryngoscope 108(2):237–242

    PubMed  Article  CAS  Google Scholar 

  26. Young-Hoon J, Dong-TI S, Jung-Hae C (2009) Factors that predict postoperative pulmonary complications after supracricoid partial laryngectomy. Arch Otolaryngol Head Neck Surg 135(11):1154–1157

    Article  Google Scholar 

  27. Laccourreye O, Laccourreye L, Garcia D, Gutierrez-Fonseca R, Brasnu D, Weinstein G (2000) Vertical partial laryngectomy versus supracricoid partial laryngectomy for selected carcinomas of the true vocal cord classified as T2N0. Ann Otol Rhinol Laryngol 109(10 Pt 1):965–971

    PubMed  CAS  Google Scholar 

  28. Karasalihoglu AR, Yagiz R, Tas A, Uzun C, Adali MK, Koten M (2004) Supracricoid partial laryngectomy with cricohyoidopexy and cricohyoidoepiglottopexy: functional and oncological results. J Laryngol Otol 118(9):671–675

    PubMed  Article  Google Scholar 

  29. Luna-Ortiz K, Nunez-Valencia ER, Carmona-Luna T (2008) Supracricoid partial laryngectomy as salvage for recurrent carcinoma of the larynx initially treated by vertical partial hemilaryngectomy. Case report. Cir Cir 76(4):333–337

    PubMed  Google Scholar 

Download references

Author information

Affiliations

  1. Southern Medical University, Guangzhou, 510515, China

    Si-Yi Zhang & Zhong-Ming Lu

  2. Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Sciences, No.106, ZhongShanEr Road, Guangzhou, 510080, China

    Si-Yi Zhang, Zhong-Ming Lu, Liang-Si Chen, Xiao-Ning Luo, Ping-Jiang Ge, Xin-Han Song & Shao-Hua Chen

  3. Guangdong Lung Cancer Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, No.106, ZhongShanEr Road, Guangzhou, 510080, China

    Yi-Long Wu

Authors
  1. Si-Yi Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Zhong-Ming Lu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Liang-Si Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Xiao-Ning Luo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ping-Jiang Ge
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Xin-Han Song
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Shao-Hua Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Yi-Long Wu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Shao-Hua Chen or Yi-Long Wu.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zhang, SY., Lu, ZM., Chen, LS. et al. Supracricoid partial laryngectomy cricohyoidoepiglottopexy (SCPL-CHEP) versus vertical partial laryngectomy for the treatment of glottic carcinoma. Eur Arch Otorhinolaryngol 270, 1027–1034 (2013). https://doi.org/10.1007/s00405-012-2241-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-012-2241-y

Keywords

  • Glottic carcinoma
  • Laryngectomy
  • Organ preservation
  • Supracricoid partial laryngectomy cricohyoidoepiglottopexy
  • Vertical partial laryngectomy