Abstract
The aim of this study was to investigate audio-vestibular function in patients with essential tremor. Twenty-three patients with essential tremor (46 ears) and 21 health control subjects (42 ears) were included in the present study. Patients and comparison subjects were matched for age and gender. All patient and control subjects underwent pure tone audiometric test, tympanogram, transient-evoked otoacoustic emissions and auditory brainstem response. Vestibular system was evaluated by bitermal caloric test. Comparison of variables between the groups was performed. Investigation of the relationship between parameters about ET disease and hearing levels were also studied. Pure tone thresholds significantly differed between patients and controls in 250 and 500 Hz frequencies (p < 0.05). There was no statistically significant difference in 1,000, 2,000, 4,000, and 6,000 Hz frequencies in essential tremor patients in comparison to the control subjects. A correlation between tremor severity and audiometric scores in low frequencies was not found. In addition, statistical analysis did not demonstrate a correlation between audiometric scores and tremor duration. The otoacoustic emission responses were found significantly different in patient and control group. The latencies of waves I, V and I–V inter-peak latencies on the ABR were not different between the groups. Our findings indicated that, abnormalities are due to cochlea rather than the retro cochlear pathology which is responsible for hearing loss associated with essential tremor.
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References
Louis ED, Ferreira JJ (2010) How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord 25(5):534–541. doi:10.1002/mds.22838
Louis ED (2010) Essential tremor as a neuropsychiatric disorder. J Neurol Sci 289(1–2):144–148. doi:10.1016/j.jns.2009.08.029
Deuschl G, Elble R (2009) Essential tremor-neurodegenerative or nondegenerative disease towards a working definition of ET. Mov Disord 24(14):2033–2041. doi:10.1002/mds.22755
Ondo WG, Sutton L (2003) Hearing impairment in essential tremor. Neurology 61:1093–1097
Karmody CS, Blevins NH, Lalwani AK (2005) Sensorineural hearing loss, early greying, and essential tremor: a new hereditary syndrome? Otolaryngol Head Neck Surg 133(1):94–99. doi:10.1016/j.otohns.2005.03.017
Benito-León J, Louis ED, Bermejo-Pareja F, Neurological disorders in Central Spain (NEDICES) study group (2007) Reported hearing impairment in essential tremor: a population-based case–control study. Neuroepidemiology 29(3–4):213–217. doi:10.1159/000112463
Deuschl G, Bain P, Brin M (1998) Consensus statement of the Movement Disorders Society on tremor. AdHoc Scientific Committee. Mov Disord 13(suppl 3):2–23
Fahn S, Tolosa E, Marin C (1993) Clinical rating scale for tremor. In: Jankovic J, Tolosa E (eds) Parkinson’s disease and movement disorders. Lippincott William & Wilkins, Baltimore, pp 271–280
Working Group on Acoustic Immittance Measurements and the Committee on Audiologic Evaluation (1990) Guidelines for screening for hearing impairment and middle ear disorders. ASHA 32(Suppl.2):17–24
Jongkees L (1948) The value of the caloric test of the labyrinth. Arch Otorhinolaryngol 48:402–417
Cohen-Mansfield J, Infeld DL (2006) Hearing aids for nursing home residents: current policy and future needs. Health Policy 79(1):4956. doi:10.1016/j.healthpol.2005.11.016
Sahin HA, Terzi M, Uçak S, Yapici O, Basoglu T, Onar M (2006) Frontal functions in young patients with essential tremor: a case comparison study. J Neuropsychiatry Clin Neurosci 18(1):64–72. doi:10.1176/appi.neuropsych.18.1.64
Akbostanci MC, Ulkatan S, Yigit A, Aydin N, Mutluer N (2000) Difference of disability between electrophysiologic subgroups of essential tremor. Can J Neurol Sci 27(1):60–64
Prosen CA, Moody DB, Stebbins WC et al (1990) Apical hair cells and hearing. Hear Res 44(2–3):179–193
Dagli M, Sivas Acar F, Karabulut H, Eryilmaz A, Erkol Inal E (2007) Evaluation of hearing and cochlear function by DPOAE and audiometric tests in patients with ankylosing spondilitis. Rheumatol Int 27(6):511–516. doi:10.1007/s00296-006-0249-6
Yılmaz S, Karalı E, Tokmak A, Güçlü E, Koçer A, Oztürk O (2009) Auditory evaluation in Parkinsonian patients. Eur Arch Otorhinolaryngol 266(5):669–671. doi:10.1007/s00405-009-0933-8
Süslü AE, Polat M, Köybaşi S, Biçer YO, Funda YO, Parlak AH (2010) Inner ear involvement in Behçet’s disease. Auris Nasus Larynx 37(3):286–290. doi:10.1016/j.anl.2009.08.006
Dagli M, Eryilmaz A, Tanrikulu S et al (2008) Evaluation of cochlear involvement by distortion product otoacoustic emission in Behçet’s disease. Auris Nasus Larynx 35(3):333–337. doi:10.1016/j.anl.2007.09.003
Acknowledgments
The authors wish to warmly thank Sefa Gültürk for statistical analysis, and Armağan İncesu for evaluation.
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The authors have no financial obligations to disclose related to this study.
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Balaban, H., Altuntaş, E.E., Uysal, İ.Ö. et al. Audio-vestibular evaluation in patients with essential tremor. Eur Arch Otorhinolaryngol 269, 1577–1581 (2012). https://doi.org/10.1007/s00405-011-1801-x
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DOI: https://doi.org/10.1007/s00405-011-1801-x