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Vestibular function in Lermoyez syndrome at attack

Abstract

Lermoyez syndrome (LS) has been regarded as a variant of Ménière’s disease (MD), but so far there have been very few cases of LS reported in the literature, so such a conclusion is debatable. Specifying the pattern of auditory and vestibular changes at attack using objective quantitative measures is important for understanding the mechanism responsible for MD and LS. Here we report the first objective measures of dynamic otolith function and dynamic semicircular canal function in an LS patient at the time of the attack as well as at quiescence, documenting the fluctuation in otolith and semicircular canal function in the patient. The very rapid changes in dynamic vestibular function at the time of the LS attack appear to complement some of the rapid changes in auditory and vestibular function at the attack in Ménière’s disease, supporting the contention that LS is a variant of MD.

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References

  1. McNeill C, Cohen MA, Gibson WPR (2009) Changes in audiometric thresholds before, during and after attacks of vertigo associated with Meniere’s syndrome. Acta Otolaryngol 129:1404–1407

    PubMed  Article  Google Scholar 

  2. Lermoyez M (1919) Le vertige qui fait entendre (Angiospasme labyrinthique). La Presse Medicale 27:1–3

    Google Scholar 

  3. Young YH, Wu CH (1994) Electronystagmographic findings in a case of Lermoyez’s syndrome. Auris Nasus Larynx 21:118–121

    PubMed  CAS  Google Scholar 

  4. Manzari L, Tedesco AR, Burgess AM, Curthoys IS (2010) Ocular and cervical vestibular-evoked myogenic potentials to bone conducted vibration in Ménière’s disease during quiescence vs during acute attacks. Clin Neurophysiol 21:1092–1101

    Article  Google Scholar 

  5. Manzari L, Tedesco AR, Burgess AM, Curthoys IS (2010) Ocular vestibular-evoked myogenic potentials to bone conducted vibration in superior vestibular neuritis show utricular function. Otolaryngol Head Neck Surg 143:274–280

    Google Scholar 

  6. Manzari L, Burgess AM, MacDougall HG, Bradshaw AP, Curthoys IS (2011) Rapid fluctuations in dynamic semicircular canal function in early Ménière’s disease. Eur Arch Otorhinolaryngol 268:637–639

    PubMed  Article  Google Scholar 

  7. Curthoys IS (2010) A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli. Clin Neurophysiol 121:132–144

    PubMed  Article  Google Scholar 

  8. Rosengren SM, Welgampola MS, Colebatch JG (2010) Vestibular evoked myogenic potentials: past, present and future. Clin Neurophysiol 121:636–651

    PubMed  Article  CAS  Google Scholar 

  9. Curthoys IS (2011) A balanced view of the evidence leads to sound conclusions. A reply to J.G. Colebatch “Sound conclusions?”. Clin Neurophysiol 121:977–988

    Article  Google Scholar 

  10. Curthoys IS, Manzari L (2011) Evidence missed. oVEMPs and cVEMPs differentiate utricular from saccular function. Otolaryngol Head Neck Surgery 144:751–752

    Google Scholar 

  11. MacDougall HG, Weber KP, McGarvie LA, Halmagyi GM, Curthoys IS (2009) The video head impulse test: diagnostic accuracy in peripheral vestibulopathy. Neurology 73:1134–1141

    PubMed  Article  CAS  Google Scholar 

  12. Fitzgerald G, Hallpike CS (1942) Studies in human vestibular function: I. observations on the directional preponderance (“Nystagmusbereitschaft”) of caloric nystagmus resulting from cerebral lesions. Brain 65:115–137

    Article  Google Scholar 

  13. Muchnik C, Hildesheimer M, Rubinstein M, Arenberg IK (1989) Low frequency air-bone gap in Ménière’s disease without middle ear pathology. A preliminary report. Am J Otolaryngol 10:1–4

    Article  CAS  Google Scholar 

  14. Yamane H, Takayama M, Sunami K, Sakamoto H, Imoto T, Anniko M (2010) Blockage of reuniting duct in Meniere’s disease. Acta Otolaryngol 130:233–239

    PubMed  Article  Google Scholar 

  15. Konishi S (1977) The ductus reuniens and utriculo-endolymphatic valve in the presence of endolymphatic hydrops in guinea-pigs. J Laryngol Otol 91:1033–1045

    PubMed  Article  CAS  Google Scholar 

  16. Uzun-Coruhlu H, Curthoys IS, Jones AS (2007) Attachment of the utricular and saccular maculae to the temporal bone. Hear Res 233:77–85

    PubMed  Article  Google Scholar 

  17. Halmagyi GM, Curthoys IS, Cremer PD, Henderson CJ, Todd MJ, Staples MJ, D’Cruz DM (1990) The human horizontal vestibulo-ocular reflex in response to high acceleration stimulation before and after unilateral vestibular neurectomy. Exp Brain Res 81:479–490

    PubMed  Article  CAS  Google Scholar 

  18. Schoonhoven R, Schmidt PH, Eggermont JJ (1990) A longitudinal electrocochleographic study of a case of long-standing bilateral Lermoyez’s syndrome. Eur Arch Otorhinolaryngol 247:333–339

    Google Scholar 

Download references

Acknowledgments

The authors are grateful for the support of National Health and Medical Research Council of Australia and the Garnett Passe and Rodney Williams Memorial Foundation. We thank an anonymous reviewer for very valuable comments and suggestions.

Conflict of interest:

One of the authors (ISC) is consultant to Otometrics but receives no financial reward for this consultancy.

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Correspondence to Leonardo Manzari.

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Manzari, L., Burgess, A.M. & Curthoys, I.S. Vestibular function in Lermoyez syndrome at attack. Eur Arch Otorhinolaryngol 269, 685–691 (2012). https://doi.org/10.1007/s00405-011-1657-0

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  • DOI: https://doi.org/10.1007/s00405-011-1657-0

Keywords

  • Vestibular
  • Lermoyez syndrome
  • Otolith
  • Semicircular canal
  • Cervical VEMP
  • Ocular VEMP
  • Vestibulo-ocular reflex
  • Ménière’s disease