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Detection of laryngeal tumors and tumoral extension by multislice computed tomography-virtual laryngoscopy (MSCT-VL)

European Archives of Oto-Rhino-Laryngology volume 266, Article number: 1953 (2009) Cite this article

Abstract

Virtual endoscopy is becoming a widely used non-invasive clinical diagnostic tool. The present study was designed to compare the sensitivity and specificity of the conventional endoscopy and virtual laryngoscopy with respect to laryngeal masses. A total of 38 patients (20 males, 18 females, mean age 61 years) with the complaint of hoarseness were included in the study. Laryngeal mucosa, lumen and mass pathology were evaluated initially by direct endoscopy and then by virtual laryngoscopy during multislice CT of the larynx. Histopathologic evaluation of the masses was also made. The main pathology of the patients was found to be laryngeal masses (60% of patients, one mass for each patient), which were polyps (n = 8), papilloma (n = 4) and carcinoma (n = 11) according to histopathologic evaluation. Retrospective evaluation of 6 lesions detected in virtual but not in conventional laryngoscopy resulted with the finding of viscous-dense mucous secretion. On the contrary, three lesions detected by conventional laryngoscopy could not be detected by virtual evaluation. A total of six patients were evaluated and considered as normal both by conventional and virtual laryngoscopic examinations. Sensitivity of the virtual laryngoscopy was 88% (23/26) while its specificity was only 50% (6/12). Positive and negative predictive values were 79% (23/29) and 66% (6/9), respectively. Accuracy of the virtual laryngoscopy was 76% (29/38). Virtual laryngoscopy is not an alternative to conventional laryngoscopy but may assist direct endoscopy without causing additional radiation exposure or discomfort to the patient. The three-dimensional contribution to interpretation of the results and subsequent manipulation of the data can be used for educational and surgical purposes.

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References

  1. Richard E, Julian G, Marc L (1991) Three dimensional high-resolution volume rendering (HRVR) of computed tomography data: applications to otolaryngology-head and neck surgery. Laryngoscope 101:573–582

    Google Scholar 

  2. Luo S, Yan Y (2005) Virtual laryngoscopy: a real-time exploration of laryngeal system based on rapid reconstruction algorithm. Proceedings of the 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference Shanghai, China

  3. Byrne AT, Walshe P, McShane D, Hamilton S (2005) Virtual laryngoscopy-preliminary experience. Eur J Radiol 56:38–42. doi:10.1016/j.ejrad.2005.02.006

    Article  CAS  PubMed  Google Scholar 

  4. Gallivan RP, Nguyen TH, Armstrong WB (1999) Head and neck computed tomography virtual endoscopy: evaluation of a new imaging technique. Laryngoscope 109:1570–1578. doi:10.1097/00005537-199910000-00005

    Article  CAS  PubMed  Google Scholar 

  5. Sagel SS, Auf der Heide JF, Aronberg DJ, Stanley RJ, Archer CR (1981) High resolution computed tomography in the staging of carcinoma of the larynx. Laryngoscope 91:292–300. doi:10.1288/00005537-198102000-00019

    Article  CAS  PubMed  Google Scholar 

  6. Castelijns JA (1991) Diagnostic radiology of head end neck oncology. Curr Opin Oncol 3:512–518. doi:10.1097/00001622-199106000-00011

    Article  CAS  PubMed  Google Scholar 

  7. Teksam M, Casey SO, Michel E, Truwit CL (2000) Real time 3D volume-rendered virtual laryngoscopy with a multi-detector CT scanning. Tani Girisim Radyol 6:361–368

    Google Scholar 

  8. Triglia JM, Nazarian B, Sudre-Levillain I, Marciano S, Moulin G, Giovanni A (2002) Virtual laryngotracheal endoscopy based on geometric surface modeling using spiral computed tomography data. Ann Otol Rhinol Laryngol 111:36–43

    PubMed  Google Scholar 

  9. Fried MP, Moharir VM, Shinmoto H et al (1999) Virtual laryngoscopy. Ann Otol Rhinol Laryngol 108:221–226

    CAS  PubMed  Google Scholar 

  10. Jolesz FA, Lorensen WE, Shinmoto H (1997) Interactive virtual endoscopy. Am J Roentgenol 169:1229–1235

    CAS  Google Scholar 

  11. Rodenwaldt J, Kopka L, Roedel R, Margas A, Grabbe E (1997) 3D virtual laryngoscopy of the upper airway: optimisation of the scan parameters in a cadaver phantom and clinical assessment. J Comput Assist Tomogr 21:405–411. doi:10.1097/00004728-199705000-00013

    Article  CAS  PubMed  Google Scholar 

  12. Rodenwaldt J, Kopka L, Roedel R, Grabbe E (1996) Three-dimensional surface imaging of the larynx and trachea by spiral CT: virtual endoscopy. Rofo 165(1):80–83

    CAS  PubMed  Google Scholar 

  13. Gluecker T, Lang F, Bessler S, Monnier P, Meuli R, Schnyder P, Duvoisin B (2001) 2D and 3D CT imaging correlated to rigid endoscopy in complex laryngo-tracheal stenoses. Eur Radiol 11(1):50–54. doi:10.1007/s003300000567

    Article  CAS  PubMed  Google Scholar 

  14. Walshe P, Hamilton S, McShane D, McConn Walsh R, Walsh MA, Timon C (2002) The potential of virtual laryngoscopy in the assessment of vocal cord lesions. Clin Otolaryngol Allied Sci 27(2):98–100. doi:10.1046/j.1365-2273.2002.00539.x

    Article  CAS  PubMed  Google Scholar 

  15. Magnano M, Bongioannini G, Cirillo S, Regge D, Martinich L, Canale G, Lerda W, Galvagno MB, Taranto F (2005) Virtual endoscopy of laryngeal carcinoma: is it useful? Otolaryngol Head Neck Surg 132(5):776–782. doi:10.1016/j.otohns.2005.01.031

    Article  PubMed  Google Scholar 

  16. El Fiky LM, AbdelMoneim HE, El Fiky SM, Eissa IM (2003) Evaluation of upper airway lesions by virtual endoscopy. Int Congr Ser 1240:1455–1459. doi:10.1016/S0531-5131(03)00831-8

    Article  Google Scholar 

  17. Luo S, McWhorter A, Yan Y (2007) Virtual laryngoscopy: a noninvasive tool for the assessment of laryngeal tumor extent. Laryngoscope 117(6):1026–1030. doi:10.1097/MLG.0b013e31804f812f

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Radiology Department, Taksim Research and Education Hospital, Istanbul, Turkey

    Mahmut Beser, M. Emin Zeybek, Bulent Öner & Varol Topçu

  2. Otorhinolaryngology Department, Namık Kemal University School of Medicine, Tekirdag, Turkey

    Erdogan Gultekin & Murat Yener

  3. Kordonboyu Mah, 9 Palmiye Sitesi, B-18 Kartal, Istanbul, Turkey

    Murat Yener

Authors
  1. Mahmut Beser
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  2. Erdogan Gultekin
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  3. Murat Yener
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  4. M. Emin Zeybek
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  5. Bulent Öner
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  6. Varol Topçu
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Correspondence to Murat Yener.

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Beser, M., Gultekin, E., Yener, M. et al. Detection of laryngeal tumors and tumoral extension by multislice computed tomography-virtual laryngoscopy (MSCT-VL). Eur Arch Otorhinolaryngol 266, 1953 (2009). https://doi.org/10.1007/s00405-009-0951-6

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  • DOI: https://doi.org/10.1007/s00405-009-0951-6

Keywords

  • Larynx
  • Virtual laryngoscopy
  • Multislice CT
  • Conventional laryngoscopy
  • Tumoral extension