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Primary combined squamous and small cell carcinoma of the larynx: report of two cases and discussion of treatment modalities

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Abstract

Combined small cell carcinoma (SMCC) of the larynx consists of SMCC admixed with a component of squamous cell carcinoma or adenocarcinoma. These tumors are very rare and, to date, only a few cases have been fully described. This points out the lack of information available about the correct management of these patients. Here, we describe two additional cases of combined SMCC of the larynx that illustrate the difficulties that we can encounter to diagnose correctly these patients and, by consequence, to treat them adequately.

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Authors and Affiliations

  1. Unité d’Oncologie Médicale, Clinique de Cancérologie Cervico-Maxillo-Faciale, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, 10, Av. Hippocrate, 1200, Brussels, Belgium

    Annelore Barbeaux, Lionel Duck, Jean-François Baurain & Jean-Pascal Machiels

  2. Department of Pathology, Clinique de Cancérologie Cervico-Maxillo-Faciale, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

    Birgit Weynand

  3. Department of Oto-Rhino-Laryngology, Clinique de Cancérologie Cervico-Maxillo-Faciale, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

    Gauthier Desuter & Marc Hamoir

  4. Department of Radiation Oncology, Clinique de Cancérologie Cervico-Maxillo-Faciale, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

    Vincent Gregoire

Authors
  1. Annelore Barbeaux
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  2. Lionel Duck
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  3. Birgit Weynand
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  4. Gauthier Desuter
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  5. Marc Hamoir
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  6. Vincent Gregoire
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  7. Jean-François Baurain
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  8. Jean-Pascal Machiels
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Correspondence to Jean-Pascal Machiels.

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Barbeaux, A., Duck, L., Weynand, B. et al. Primary combined squamous and small cell carcinoma of the larynx: report of two cases and discussion of treatment modalities. Eur Arch Otorhinolaryngol 263, 786–790 (2006). https://doi.org/10.1007/s00405-006-0060-8

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  • DOI: https://doi.org/10.1007/s00405-006-0060-8

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