Skip to main content

Advertisement

SpringerLink
Log in

Classic (Mediterranean) Kaposi’s sarcoma of the true vocal cord: a case report and review of the literature

  • Head and Neck Oncology
  • Published:
European Archives of Oto-Rhino-Laryngology and Head & Neck Aims and scope Submit manuscript

Abstract

Kaposi’s sarcoma (KS) is a rare subcutaneous lesion linked mainly with patients suffering from acquired immunodeficiency syndrome. The aim of the present study is to present the first documented case of classic Kaposi’s sarcoma (CKS) located in the right true vocal cord. A 62 year old male presented with cough and hoarseness for 2 months. Clinical examination revealed a nodule on the right vocal cord. The patient underwent surgery and the lesion was removed and biopsied. The histopathology report showed that the lesion was KS but with no complete removal of the lesion, since the surgical margins of the nodule were not healthy. The patient, although fully informed, refused any further treatment. Further laboratory tests were performed, revealing an HIV-negative immunodeficiency profile. Although (Mediterranean) CKS is not an aggressive malignancy, surgery with complete removal of the affected area is indicated when it is applicable. Moreover, conservative treatment and follow up of the patient is essential in order to prevent relapse or other primary lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Kaposi M (1872) Idiopathisches multiples Pigmentsarkom der Haut. Arch Dermatol Syph (Prague) 4:265–273

    Article  Google Scholar 

  2. Köbner H (1869) Zur Kenntnis der allgemeinen Sarkomatose und der Hautsarkome im besonderen. Arch Dermatol Syph 1:369–381

    Article  Google Scholar 

  3. Friedman-Kien AE (1981) Disseminated Kaposi’s sarcoma syndrome in young homosexual men. J Am Acad Dermatol 5(4):468–471

    Article  PubMed  CAS  Google Scholar 

  4. Borkovic SP, Schwartz RA (1981) Kaposi’s sarcoma presenting in the homosexual man—a new and striking phenomenon! Ariz Med 38(12):902–904

    PubMed  CAS  Google Scholar 

  5. Costa J, Rabson AS (1983) Generalized Kaposi’s sarcoma is not a neoplasm. Lancet 1(8314–8315):58

    Article  PubMed  CAS  Google Scholar 

  6. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS (1994) Identification of herpes virus-like DNA sequences in AIDS-associated Kaposi’s sarcoma. Science 266:1865

    Google Scholar 

  7. Iscovich J, Boffetta P, Franceschi S (2000) Classic Kaposi sarcoma: epidemiology and risk factors. Cancer 88(3):500–517

    Article  PubMed  CAS  Google Scholar 

  8. Centers for disease control (1999) Surveillance for AIDS-defining opportunistic illnesses, 1992–1997. MMWR 48(SS2):1–22

    Google Scholar 

  9. Dezube BJ (2000) Acquired immunodeficiency syndrome-related Kaposi’s sarcoma: clinical features, staging, and treatment. Semin Oncol 27(4):424–430

    PubMed  CAS  Google Scholar 

  10. Touloumi G, Kaklamanis L, Potouridou I, Katsika-Hatziolou E, Stratigos J, Mueller N, Hatzakis A (1997) The epidemiologic profile of Kaposi’s sarcoma in Greece prior to and during the AIDS era. Int J Cancer 70(5):538–541

    Article  PubMed  CAS  Google Scholar 

  11. Stratigos J, Potouridou I, Katoulis A, Hatziolou E, Christofidou E, Stratigos A, Hatzakis A, Stavrianeas NG (1997) Classic Kaposi’s sarcoma in Greece: a clinico-epidemiological profile. Int J Dermatol 36(10):735–740

    Article  PubMed  CAS  Google Scholar 

  12. Reynolds WA, Winkelmann RK, Soule EH (1965) Kaposi’s sarcoma: a clinicopathologic study with particular reference to its relationship to the reticuloendothelial system. Medicine (Baltimore) 44(5):419–443

    Article  CAS  Google Scholar 

  13. Abramson Al, Simons RL (1970) Kaposi sarcoma of the head and neck. Arch Otolaryngol 92(5):505–507

    PubMed  Google Scholar 

  14. Moritsch E, Jarisch R, Konrad K (1978) Kaposi’s sarcoma. Pharyngo-laryngeal manifestation, treatment. Laryngol Rhinol Otol (Stuttg) 57(9):792–796

    CAS  Google Scholar 

  15. Abemayor E, Calcaterra TC (1983) Kaposi’s sarcoma and community-acquired immunodeficiency syndrome. Arch Otolaryngol 109(8):536–542

    PubMed  CAS  Google Scholar 

  16. Friedman M, Venkatesan TK, Caldarelli DD (1996) Intralesional vinblastine for treating AIDS-associated Kaposi’s sarcoma of the oropharynx and larynx. Ann Otol Rhinol Laryngol 105(4):272–274

    PubMed  CAS  Google Scholar 

  17. Mochloulis G, Irving RM, Grant HR, Miller RF (1996) Laryngeal Kaposi’s sarcoma in patients with AIDS. J Laryngol Otol 110(11):1034–1037

    Article  PubMed  CAS  Google Scholar 

  18. Schiff NF, Annino DJ, Woo P, Shapshay S (1997) Kaposi’s sarcoma of the larynx. Ann Otol Rhinol Laryngol 106(7 Pt. 1):563–567

    PubMed  CAS  Google Scholar 

  19. Coyas A, Eliadellis E, Anastassiades O (1983) Kaposi’s sarcoma of the larynx. J Laryngol Otol 97(7):647–649

    Article  PubMed  CAS  Google Scholar 

  20. Nikolaidis V, Nalbantian M, Nikolaou A, Daniilidis I (1998) Oropharyngeal Kaposi sarcoma non-relative to HIV-infection; a case report. Hell Otorhinolaryngol Head Neck Surg 2:37–39

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Otorhinolaryngology Department, AHEPA University Hospital, Aristotle University of Thessaloniki, 540 06, Thessaloniki, Greece

    N. Angouridakis, J. Constantinidis, K. Vlachtsis, K. Mpouras & J. Daniilidis

  2. Department of Pathology, Aristotle University of Thessaloniki, Thessaloniki, Greece

    G. Karkavelas

Authors
  1. N. Angouridakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Constantinidis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. Karkavelas
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Vlachtsis
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K. Mpouras
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J. Daniilidis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. Angouridakis.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Angouridakis, N., Constantinidis, J., Karkavelas, G. et al. Classic (Mediterranean) Kaposi’s sarcoma of the true vocal cord: a case report and review of the literature. Eur Arch Otorhinolaryngol 263, 537–540 (2006). https://doi.org/10.1007/s00405-006-0007-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00405-006-0007-0

Keywords

Search

Navigation