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Oncocytic carcinoma of the maxillary sinus: a rare neoplasm

  • Head and Neck Oncology
  • Published:
European Archives of Oto-Rhino-Laryngology and Head & Neck Aims and scope Submit manuscript

Abstract

Oncocytic neoplasms are tumors composed of oncocytes (i.e., epithelial cells with a large cytoplasm that is rich in mitochondria). Most cases are benign and originate from the major salivary glands, while the minor salivary glands are rarely involved. Occurrence of oncocytic carcinoma (or malignant oncocytoma) within the sinonasal tract is an unusual event. We report a rare case of maxillary sinus oncocytic carcinoma occurring in a 45-year-old male. Biopsy was consistent with an unspecified salivary gland neoplasm. The patient underwent total maxillectomy through a lateral rhinotomic approach; hard palate reconstruction with temporal myofascial flap was performed. Definitive histology was consistent with oncocytic carcinoma. Due to the local extension of the lesion, postoperative radiotherapy (60 Gy) was delivered. Three years after surgery, the patient is free from disease. A brief analysis of the literature was also accomplished in order to discuss treatment options and prognosis of this unusual neoplasm.

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References

  1. Chui RT, Liao SY, Bosworth H (1985) Recurrent oncocytoma of the ethmoid sinus with orbital invasion. Otolaryngol Head Neck Surg 93:267–270

    PubMed  CAS  Google Scholar 

  2. Cohen MA, Batsakis JG (1968) Oncocytic tumors (oncocytomas) of the minor salivary glands. Arch Otolaryngol 88:97–99

    Google Scholar 

  3. Corbridge RJ, Gallimore AP, Dalton CG, O’Flynn PE (1996) Oncocytomas of the upper jaw. Head Neck 18:374–380

    Article  PubMed  CAS  Google Scholar 

  4. Ellis LG, Auclair PL (1995) Tumors of the salivary glands. In: Atlas of tumor pathology, 3rd series. Armed Forces Institute of Pathology, Washington, DC, pp 103–114

  5. Ellis LG, Auclair PL (1995) Tumors of the salivary glands. In: Atlas of tumor pathology, 3rd series. Armed Forces Institute of Pathology, Washington, DC, pp 318–324

  6. Ellis LG, Auclair PL, Gnepp D, Goode RK (1991) Surgical pathology of the salivary gland. WB Saunders, Philadelphia, pp 455–464

    Google Scholar 

  7. Fayet B, Bernard JA, Zachar D, D’Hermies F, Janot F, Pigeau I, Pouliquen Y (1990) Malignant nasal oncocytoma disclosed by mucocele of the lacrimal sac with hemolacrimia. J Fr Ophthalmol 13:153–158

    CAS  Google Scholar 

  8. Goode RK (1991) Oncocytoma. In: Ellis GL, Auclair PL, Gnepp DR (eds) Surgical pathology of the salivary gland. WB Saunders, Philadelphia, pp 225–237

    Google Scholar 

  9. Gray SR, Cornog JL, Sook IS (1976) Oncocytic neoplasms of salivary glands: a report of fifteen cases including two malignant oncocytomas. Cancer 38:1306–1317

    Article  PubMed  CAS  Google Scholar 

  10. Guclu E, Oghan F, Ozturk O, Alper M, Egeli E (2005) A rare malignancy of the parotid gland: oncocytic carcinoma. Eur Arch Otorhinolaryngol 262:567–569

    Article  PubMed  Google Scholar 

  11. Hamperl H (1931) Beitrage zur normalen und pathologischen histologie menschlicher speicheldrusen. Zeitschrift fur mikroskopisch anatomische Forschung 27:1–55

    Google Scholar 

  12. Hamperl H (1962) Oncozytome der speicheldrusen. Z Krebsforsch 64:427–440

    Article  PubMed  CAS  Google Scholar 

  13. Hamperl H (1962) Benign and malignant oncocytoma. Cancer 15:1019–1027

    Article  PubMed  CAS  Google Scholar 

  14. Handler SD, Ward PH (1979) Oncocytoma of the maxillary sinus. Laryngoscope 89:372–376

    Article  PubMed  CAS  Google Scholar 

  15. Harrison D, Lund VJ (1993) Tumours of the upper jaw. Churchill Livingstone, London, pp 108–110

    Google Scholar 

  16. Johns ME, Batsakis JG, Short CD (1973) Oncocytic and oncocytoid tumours of the salivary glands. Laryngoscope 83:1940–1952

    Article  PubMed  CAS  Google Scholar 

  17. Johnson DiMaio H, DiMaio VJM, DiMaio TM, Nicastri AD, Chen CK (1980) Oncocytic carcinoma of the nasal cavity. South Med J 73:803–806

    PubMed  Google Scholar 

  18. Mahmoud NA (1979) Malignant oncocytoma of the nasal cavity. J Laryngol Otol 93:729–734

    PubMed  CAS  Google Scholar 

  19. Martin H, Janda J, Behrbohm H (1990) Locally invasive oncocytoma in the nasal cavity. Zentralbl Allg Pathol 136:703–706

    PubMed  CAS  Google Scholar 

  20. Mikhail RA, Reed DN, Bybee DB, Okoye MI, Dodds ME (1988) Malignant oncocytoma of the maxillary sinus: an ultrastructural study. Head Neck Surg 10:427–431

    Article  PubMed  CAS  Google Scholar 

  21. Savic D, Djeric D, Jasovic A (1989) Oncocytoma of the nose and the ethmoidal and sphenoidal sinuses. Rev Laryngol 110:481–483

    CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Otorhinolaryngology, University of Brescia, Piazza Spedali Civili 1, 25123, Brescia, Italy

    Davide Lombardi, Michela Piccioni & Piero Nicolai

  2. Department of Radiology, University of Brescia, Piazza Spedali Civili 1, 25123, Brescia, Italy

    Davide Farina

  3. Department of Pathology, University of Brescia, Piazza Spedali Civili 1, 25123, Brescia, Italy

    Maria Laura Morassi

Authors
  1. Davide Lombardi
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  2. Michela Piccioni
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  3. Davide Farina
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  4. Maria Laura Morassi
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  5. Piero Nicolai
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Correspondence to Piero Nicolai.

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Lombardi, D., Piccioni, M., Farina, D. et al. Oncocytic carcinoma of the maxillary sinus: a rare neoplasm. Eur Arch Otorhinolaryngol 263, 528–531 (2006). https://doi.org/10.1007/s00405-005-0004-8

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  • DOI: https://doi.org/10.1007/s00405-005-0004-8

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