Abstract
The solitary fibrous tumor is an uncommon unilateral benign lesion that usually arises from the pleura. Recently, these tumors have been described in many other locations, such as the mediastinum, head and neck, orbit and urogenital system. To date, only two cases of solitary fibrous tumor arising from the larynx have been reported in the scientific literature. We describe a new case of laryngeal solitary fibrous tumor localized at the right false vocal fold. A 29-year-old man presented with a 6-month history of progressive hoarseness and foreign body sensation in the throat. A mass lesion was recognized in the right false vocal fold, and CT scan demonstrated a large, well-defined tumor without signs of infiltration. The tumor was removed by transoral CO2 laser surgery. The definitive diagnosis was obtained by immunohistochemical analysis that showed vimentin and CD34-positive cells. The patient remains free of tumor after 15 months of follow-up.
Similar content being viewed by others
References
Nielsen GP, O’Connell JX, Dickersin GR, Rosenberg AE (1997) Solitary fibrous tumor of soft tissue: a report of 15 cases, including 5 malignant examples with light microscopic, immunohistochemical, and ultrastructural data. Mod Pathol 10:1028–1037
Piattelli A, Fioroni M, Rubini C (1998) Solitary fibrous tumor of the tongue. Oral Oncol 34:431–434
Alobid I, Alos L, Blanch JL, Benitez P, Bernal-Sprekelsen M, Mullol J (2003) Solitary fibrous tumor of the nasal cavity and paranasal sinuses. Acta Otolaryngol 123:71–74
Sato J, Asakura K, Yokoyama Y, Satoh M (1998) Solitary fibrous tumor of the parotid gland extending to the parapharyngeal space. Eur Arch Otorhinolaryngol 255:18–21
Safneck JR, Alguacil-Garcia A, Dort JC, Phillips SM (1993) Solitary fibrous tumor: report of two new locations in the upper respiratory tract. J Laryngol Otol 107:252–256
Benlyazid A, Lescanne E, Lefrancq T, Fetissoff F, Beutter P (1998) Solitary fibrous tumor of the larynx: report of case. J Laryngol Otol 112:286–289
England D, Hochholzer L, McCarthy M (1989) Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol 13:640–658
Ron D, Powers A, Pandian M, Godine J, Axelrod L (1989) Increased insulin-like growth factor II production and consequent suppression of growth hormone secretion: a dual mechanism for tumor-induced hypoglycemia. J Clin Endocrinol Metab 68:701–706
Okike N, Bernatz P, Woolner L (1978) Localized mesothelioma of the pleura. Benign and malignant variants. J Thorac Cardiovasc Surg 75:363–372
Batsakis JG, Hybels RD, El Naggar AK (1993) Solitary fibrous tumor. Ann Otol Rhinol Laryngol 102:74–76
Kim TA, Brunberg JA, Pearson JP, Ross DA (1996) Solitary fibrous tumor of the paranasal sinuses: CT and MR appearance. AJNR 17:1767–1772
Sandvliet RH, Heysteeg M, Paul MA (2000) A large thoracic mass in a 57-year-old patient. Solitary fibrous tumor of the pleura. Chest 117:897–900
Brunnemann RB, Ro JY, Ordonez NG, Mooney J, El-Naggar A, Ayala AG (1999) Extrapleural solitary fibrous tumor: a clinicopathologic study of 24 cases. Mod Pathol 12:1034–1042
Mena H, Ribas JL, Pezeshkpour GH, Cowan DN, Parisi JE (1991) Hemangiopericytoma of the central nervous system: a review of 94 cases. Hum Pathol 22:84–91
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Alobid, I., Alós, L., Maldonado, M. et al. Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report. Eur Arch Otorhinolaryngol 262, 286–288 (2005). https://doi.org/10.1007/s00405-004-0805-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00405-004-0805-1