Abstract.
4 patients with recurrent gynecological malignancy were treated photodynamically, 4 d after sensitisation with intravenous meso-tetra(hydroxyphenyl)chlorin (m-THPC) at a dose of 0.15 mg/kg bodyweight (total dose ranged from 12–15 mg). Light at 652 nm was derived from a KTP-Dye laser (Diasonic) and delivered superficially at a total light dose of 20 J/cm2 (power density of 100 mW/ sec). Within 24 h necrosis occurred which was restricted to the tumor area. There was serious bleeding occurred in 1 patient. All tumors responded to PDT, however woundhealing was significantly delayed and survival times were disappointingly short.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: August 1998 / Accepted: 14 December 1998
Rights and permissions
About this article
Cite this article
Krimbacher, E., Zeimet, A., Marth, C. et al. Photodynamic therapy for recurrent gynecologic malignancy: a report on 4 cases. Arch Gynecol Obstet 262, 193–197 (1999). https://doi.org/10.1007/s004040050249
Issue Date:
DOI: https://doi.org/10.1007/s004040050249