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Recurrent failure of pronucleus formation after intracytoplasmic sperm injection

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Abstract.

We report on a couple with complete fertilization failure in three consecutive trials of intracytoplasmic sperm injection. Some of the unfertilized oocytes were fixed and decondensed sperm heads were found in all of them. It is not clear whether specific defects of the oocyte, abnormalities of sperm chromatin, or a combination of factors are responsible for the observed failure to develop pronuclei.

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Authors and Affiliations

  1. Department of Gynecology and Obstetrics (Chairman: Prof. Dr. R. Kreienberg), University of Ulm, Prittwitzstraße 43, D-89075 Ulm, , , , ,

    B. E. Rosenbusch

  2. Laboratory for Medical Genetics Dr. Tettenborn, Friedenstraße 1, D-89073 Ulm, , , , ,

    M. Schneider

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  1. B. E. Rosenbusch
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  2. M. Schneider
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Received: 22 August 1998 / Accepted: 22 September 1998

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Rosenbusch, B., Schneider, M. Recurrent failure of pronucleus formation after intracytoplasmic sperm injection. Arch Gynecol Obstet 262, 185–188 (1999). https://doi.org/10.1007/s004040050247

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  • DOI: https://doi.org/10.1007/s004040050247

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