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Comparison of clinical outcomes and second-look hysteroscopy of the complete and incomplete septate uterus after hysteroscopic septoplasty

  • General Gynecology
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Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Septate uterus is the most common congenital uterine malformation. This retrospective cohort study compared clinical outcomes and second-look hysteroscopy findings in patients with complete and incomplete septate uteri after septoplasty.

Methods

We reviewed the medical records of patients with a septate uterus who underwent hysteroscopic septoplasty and second-look hysteroscopy at the West China Second University Hospital between September 2013 and September 2021. Information regarding pregnancy outcomes was collected through telephone interviews. The independent samples t-test, Mann–Whitney U test, Pearson’s chi-square test, and Fisher’s exact test were used to explore the differences between the complete and incomplete septate uterus groups.

Results

A total of 64 patients were enrolled in this study. There was no significant difference in intrauterine adhesion (IUA) rates (16.7% and 32.1%), pregnancy rates (44.1% and 42.9%), term delivery rates (35.3% and 32.1%), premature delivery rates (2.9% and 0), placenta previa rates (2.9% and 3.6%), placenta implantation/adhesion rates (5.9% and 3.6%), and premature rupture of membranes rates (2.9% and 0) between the complete and the incomplete group after hysteroscopic septoplasty (P > 0.05). Endometrial polyps in the septate uterus were common, with an incidence of 33.3% and 25% in the complete and incomplete groups, respectively (P > 0.05).

Conclusion

The pregnancy outcomes of complete and incomplete septate uteri after hysteroscopic septoplasty were similar. There was no statistical difference in IUAs after surgery. Different treatment strategies may not be required for complete or incomplete septate uteri.

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Data availability

Data available on request.

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Funding

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Author information

Author notes

  1. Wei Xiong and Xin Tan contributed to the work equally and should be regarded as co-first authors.

Authors and Affiliations

  1. Day Surgery Department, West China Second University Hospital, Sichuan University, No. 20, 3rd Section, South Renmin Road, Chengdu, 610041, Sichuan, China

    Wei Xiong, Xin Tan, Yana Liu, Jie Liu, Xue Dong, Zhilin Wang & Hengxi Chen

  2. Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, No. 20, 3rd Section, South Renmin Road, Chengdu, 610041, Sichuan, China

    Wei Xiong, Xin Tan, Yana Liu, Jie Liu, Xue Dong, Zhilin Wang & Hengxi Chen

  3. Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Sichuan, 610041, China

    Wei Xiong, Xin Tan, Yana Liu, Jie Liu, Xue Dong, Zhilin Wang & Hengxi Chen

Authors
  1. Wei Xiong
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Contributions

HC and WX assisted in conception and design of study. XD, YL, JL, ZW, and XT contributed to acquisition of data. HC, WX and XT analyzed and interpreted the data. HC and WX drafted the manuscript. XT and HC revised the manuscript. All the authors approved the final version.

Corresponding author

Correspondence to Hengxi Chen.

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Conflict of interest

The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

This retrospective study was approved by the Institutional Review Board of West China Second University Hospital.

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Informed consent was obtained from all individual participants included in this study.

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Xiong, W., Tan, X., Liu, Y. et al. Comparison of clinical outcomes and second-look hysteroscopy of the complete and incomplete septate uterus after hysteroscopic septoplasty. Arch Gynecol Obstet 309, 227–233 (2024). https://doi.org/10.1007/s00404-023-07243-x

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