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Umbilical cord blood gases sampling in low-risk vaginal deliveries as a predictor of adverse neonatal outcome

  • Maternal-Fetal Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Introduction

There is no clear correlation between abnormal umbilical cord blood gas studies (UCGS) and adverse neonatal outcome in low-risk deliveries. We investigated the need for its routine use in low-risk deliveries.

Methods

We retrospectively compared maternal, neonatal, and obstetrical characteristics among low-risk deliveries (2014–2022) between “normal” and “abnormal” pH groups: A:normal pH ≥ 7.15; abnormal pH < 7.15; B: normal pH ≥ 7.15 and base excess (BE) > − 12 mmol/L; abnormal pH < 7.15 and BE ≤ We retrospectively compared 12 mmol/L; C: normal pH ≥ 7.1; abnormal pH < 7.1; D: normal pH > 7.1 and BE > − 12 mmol/L; abnormal pH < 7.1 and BE ≤ − 12 mmol/L.

Results

Of 14,338 deliveries, the rates of UCGS were: A—0.3% (n = 43); B—0.07% (n = 10); C—0.11% (n = 17); D—0.03% (n = 4).

The primary outcome, composite adverse neonatal outcome (CANO) occurred in 178 neonates with normal UCGS (1.2%) and in only one case with UCGS (2.6%). The sensitivity and specificity of UCGS as a predictor of CANO were high (99.7–99.9%) and low (0.56–0.59%), respectively.

Conclusion

UCGS were an uncommon finding in low-risk deliveries and its association with CANO was not clinically relevant. Consequently, its routine use should be considered.

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Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

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Authors

Contributions

EB: project development, data collection and management, data analysis, manuscript writing and editing. NG: project development, data collection and management, data analysis, manuscript writing and editing. IC: project development, data collection and management, data analysis, manuscript writing and editing. AS: project development. DJ: data collection. GB: project development. OG: data analysis. Eran Weiner: project development, data collection and management, data analysis, manuscript writing and editing.

Corresponding author

Correspondence to Elad Barber.

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The authors declare no competing financial interests.

Ethics approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval number # 0215-20-WOMC dated 22.09.2020.

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This was a retrospective study; consent was not needed.

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Gonen, N., Cohen, I., Gluck, O. et al. Umbilical cord blood gases sampling in low-risk vaginal deliveries as a predictor of adverse neonatal outcome. Arch Gynecol Obstet 309, 523–531 (2024). https://doi.org/10.1007/s00404-023-06965-2

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  • DOI: https://doi.org/10.1007/s00404-023-06965-2

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