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Review on current treatment options for lesions of uncertain malignant potential (B3 lesions) of the breast: do B3 papillary lesions need to be removed in any case by open surgery?

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Abstract

Background

In breast tissue, pre-malignant lesions are classified as BIRADS 3. The treatment of this heterogeneous group varies with expertise and tools available.

Materials and methods

With the example of two case reports, the literature is reviewed on current treatment options for BIRADS 3 breast lesions.

Results

About 7% of all B-type breast biopsies fall into the B3 category. Approximately 35% of these B3 lesions are due to FEA, 20% to PLs and another 20% to ADH. Due to improvement in diagnostics, the incidence is increasing, while their value as a predictive factor for malignancy has steadily been fallen.

Conclusion

Depending on the histology of the needle biopsy, a complete resection with vacuum-assisted biopsy may be a treatment alternative to open biopsy.

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Authors and Affiliations

Authors

Contributions

IB: methodology, equal writing—review and editing, and supporting. AdG: conceptualization, equal resources, equal writing—original draft, and supporting. AdW: data curation, supporting writing—review and editing, and supporting. AN: resources, equal writing—original draft, and supporting. JdW: conceptualization, equal project administration, supporting writing—review and editing, equal conceptualization, equal project administration, supporting writing—review and editing, and equal. JW: resources, supporting supervision, equal writing—review and editing, and supporting. FE: conceptualization, lead formal analysis, equal methodology, equal project administration, lead writing—original draft, and lead.

Corresponding author

Correspondence to Florian Ebner.

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The authors declare no conflict of interest.

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Bekes, I., deGregorio, A., deWaal, A. et al. Review on current treatment options for lesions of uncertain malignant potential (B3 lesions) of the breast: do B3 papillary lesions need to be removed in any case by open surgery?. Arch Gynecol Obstet 300, 481–484 (2019). https://doi.org/10.1007/s00404-018-4985-0

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  • DOI: https://doi.org/10.1007/s00404-018-4985-0

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