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RETRACTED ARTICLE: Maternal and fetal outcome in women with rheumatic heart disease: a 3-year observational study

  • Maternal-Fetal Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

This article was retracted on 20 May 2022

This article has been updated

Abstract

Objective

To assess prospectively the maternal and fetal outcome in women with rheumatic heart disease (RHD).

Methods

This was a prospective 3-year observational study carried out at Menoufia University Hospital, Egypt in which 192 patients out of 9856 pregnant women were diagnosed with RHD and divided into two groups: low- and high-risk groups based on the New York Heart Association (NYHA) functional classification. Enrolled patients were followed to assess the maternal and fetal outcome.

Results

Mitral valve disease was the commonest single valve (118/192, 51.4 %) affected by rheumatic fever. Cardiac women with NYHA class I&II characterized by having fewer pulmonary hypertension, taking cardiac medications, prior heart failure and prior cardiac surgery than those with NYHA class III&IV. On the hand, cardiac women with NYHA III&IV have poorer maternal outcome with more complications as heart failure, arrhythmias, thromboembolism, admission to cardiac ICU, delivery by cesarean section and defective lactation. Prematurity and NICU admission were significantly more in NYHA III&IV.

Conclusions

RHD still constitutes a major cause of maternal and fetal morbidity and mortality. Multidisciplinary cooperation, proper preconception and antenatal care are the key measures to improve the outcomes of these patients.

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References

  1. Arnoni RT, Arnoni AS, Bonini RC, de Almeida AF, Neto CA, Dinkhuysen JJ et al (2003) Risk factors associated with cardiac surgery during pregnancy. Ann Thorac Surg 76(5):1605–1608

    Article  Google Scholar 

  2. Carapetis JR, Steer AC, Mulholland EK (2004) The current evidence for the burden of group A streptococcal diseases (WHO/FCH/CAH/05.07). World Health Organization, Geneva

    Google Scholar 

  3. Rheumatic fever and rheumatic heart disease: report of a WHO expert consultation—Geneva, 29 October–1 November 2001. WHO Technical Report Series 2001, p 923. http://www.who.int/cardiovascular_diseases/resources/en/cvd_trs923.pdf

  4. Konar H, Chaudhuri S (2012) Pregnancy complicated by maternal heart disease: a review of 281 women. J Obstet Gynaecol India 62(3):301–306

    Article  Google Scholar 

  5. Essop MR, Nkomo VT (2005) Rheumatic and nonrheumatic valvular heart disease: epidemiology, management, and prevention in Africa. Circulation 112:3584–3591

    Article  Google Scholar 

  6. Siu SC, Sermer M, Colman JM et al (2001) Prospective multi-center study of pregnancy outcomes in women with heart disease. Circulation 104:515–521

    Article  CAS  Google Scholar 

  7. Carapetis JR, Steer AC, Mulholland EK, Weber M (2005) The global burden of group A streptococcal diseases. Lancet Infect Dis 5:685–694

    Article  Google Scholar 

  8. Remenyi B, Wilson N, Steer A, Ferreira B, Kado J, Kumar K et al (2012) World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease—an evidence-based guideline. Nat Rev Cardiol 9:297–309

    Article  Google Scholar 

  9. Enriquez-Sarano M, Akins CW, Vahanian A (2009) Mitral regurgitation. Lancet 373:1382–1394

    Article  Google Scholar 

  10. Bhandari S, Subramanyam K, Trehan N (2007) Valvular heart disease: diagnosis and management. J Assoc Physicians India 55:575–584

    PubMed  Google Scholar 

  11. Baskerville CA, Hanrahan BB, Burke AJ, Holwell AJ, Remond MG, Maguire GP (2012) Infective endocarditis and rheumatic heart disease in the north of Australia. Heart Lung Circ 21:36–41

    Article  Google Scholar 

  12. Stout KK, Otto CM (2007) Pregnancy in women with valvular heart disease. Heart 93:552–558

    Article  Google Scholar 

  13. Lesniak-Sobelga A, Tracz W, KostKiewicz M, Podolec P, Pasowicz M (2004) Clinical and echocardiographic assessment of pregnant women with valvular heart diseases—maternal and fetal outcome. Int J Cardiol 94:15–23

    Article  Google Scholar 

  14. Madazli R, Sal V, Cift T, Guralp O, Goymen A (2010) Pregnancy outcomes in women with heart disease. Arch Gynecol Obstet 281(1):29–34

    Article  Google Scholar 

  15. Subbaiah M, Sharma V, Kumar S et al (2013) Heart disease in pregnancy: cardiac and obstetric outcomes. Arch Gynecol Obstet 288(1):23–27

    Article  Google Scholar 

  16. Sciscione AC, Ivester T, Largoza M et al (2003) Acute pulmonary oedema in pregnancy. Obstet Gynaecol 101(3):511–515

    Google Scholar 

  17. Eisenberg MJ (1993) Rheumatic heart disease in the developing world: prevalence, prevention and control. Eur Heart J 14:122–128

    Article  CAS  Google Scholar 

  18. Liu H, Xu JW, Zhao XD, Ye TY, Lin JH, Lin QD (2010) Pregnancy outcomes in women with heart disease. Chin Med J (Engl) 123(17):2324–2330

    Google Scholar 

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Acknowledgments

The authors would like to acknowledge the contribution of the residents and nursing staff of the outpatient clinics and delivery ward of Menoufia university Hospital.

Authors’ contribution

Mohamed Rezk: Project development, Data Collection, Manuscript writing. Awni Gamal: Data collection.

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Correspondence to Mohamed Rezk.

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Rezk, M., Gamal, A. RETRACTED ARTICLE: Maternal and fetal outcome in women with rheumatic heart disease: a 3-year observational study. Arch Gynecol Obstet 294, 273–278 (2016). https://doi.org/10.1007/s00404-015-3990-9

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  • DOI: https://doi.org/10.1007/s00404-015-3990-9

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