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Uterine artery embolization combined with intra-arterial MTX infusion: its application in treatment of cervical pregnancy

Archives of Gynecology and Obstetrics volume 293, pages 1043–1047 (2016)Cite this article

Abstract

Objective

To investigate the efficacy and safety of uterine artery chemoembolization (UAE) combined with intra-arterial MTX infusion for the treatment of cervical pregnancy.

Methods

Retrospective chart review for 26 cervical pregnancy patients treated at Renji hospital between January 2000 and December 2012. 14 patients received UAE combined with intra-arterial MTX infusion (UAE group) and 12 patients received single intramuscular MTX injection combined with subsequent uterine curettage (non-UAE group).

Results

All 14 patients in the UAE group were treated successfully and 1 patient in the non-UAE group had 1200 ml vaginal bleeding during uterine curettage and was then treated with emergency UAE. The mean estimated blood loss during uterine curettage in the UAE group was much less than in non-UAE Group. A quicker regression of serum β-hCG level and normal menses resumed and a shorter hospital stay were observed in the UAE group than in the non-UAE group.

Conclusions

Uterine artery chemoembolization combined with intra-arterial MTX infusion is an efficient conservative treatment for cervical pregnancy.

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Abbreviations

UAE:

Uterine artery chemoembolization

MTX:

Methotrexate

IVF:

In vitro fertilization

LEEP:

Loop electrocautery excision procedures

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Affiliations

  1. Department of Obstetrics and Gynecology, RenJi Hospital, Shanghai Jiao-Tong University School of Medicine, 1630 Dong Fang Road, Shanghai, 200127, China

    Shu Zhang, Huan Yan & Wen-ting Ji

Authors
  1. Shu Zhang
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  2. Huan Yan
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  3. Wen-ting Ji
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Corresponding author

Correspondence to Shu Zhang.

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All authors declare that we have no conflict of interest. All authors declare we have full control of all primary data and we agree to allow the journal to review the data if requested.

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Zhang, S., Yan, H. & Ji, Wt. Uterine artery embolization combined with intra-arterial MTX infusion: its application in treatment of cervical pregnancy. Arch Gynecol Obstet 293, 1043–1047 (2016). https://doi.org/10.1007/s00404-015-3929-1

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  • DOI: https://doi.org/10.1007/s00404-015-3929-1

Keywords

  • Cervical pregnancy
  • Uterine artery embolization
  • Methotrexate