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Fertility, pregnancy outcomes and deliveries following myomectomy: experience of a French Caribbean University Hospital

  • Gynecologic Endocrinology and Reproductive Medicine
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Background

Myoma is the most common benign tumor in women of childbearing age, with a high frequency in Afro-Caribbean than in other women. Depending on their number, size and location, myomas are suspected to be a cause of infertility. Conservative treatment by myomectomy is possible for symptomatic patients wishing to preserve their fertility.

Purpose

The aim of this study was to evaluate the fertility of patients undergoing myomectomy in the University Hospital of Pointe-à-Pitre, Guadeloupe.

Methods

We conducted a retrospective study including all patients under age 42 who had conservative surgery from January 1st, 2005 to December 31st, 2009. The main judgment criteria were the occurrence of postoperative pregnancy and its outcome.

Results

Of 297 operated patients, 220 were interviewed by phone (74.1 %), 124 (56.3 %) had tried to obtain a pregnancy and 54 patients (43.5 %) had 66 pregnancies (59.1 % being live births and 25.8 % miscarriages). For fertility after surgery, univariate analysis identified the number (more than 6, P = 0.0027) and an intramural location (P = 0.027) of myomas as negative factors and multivariate analysis identified age (over 35 years, RR = 2.45) and the association of other causes of infertility (RR = 2.21) as negative factors for pregnancy.

Conclusion

The modest conception rate (43.5 %) after myomectomy among those women trying to obtain a pregnancy may be linked to the specificities of our population, and in particular its relatively high age and the frequent association of multiple causes of infertility.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, University Hospital of Pointe-à-Pitre/Abymes, Route de Chauvel, BP 465, 97159, Pointe-à-Pitre cedex, Guadeloupe, France

    Daphné Borja de Mozota, Philippe Kadhel & Eustase Janky

  2. Institut National de la Santé et de la Recherche Médicale Inserm U1085, IRSET, Campus universitaire de Fouillole, BP 250, 97157, Pointe-à-Pitre cedex, Guadeloupe, France

    Philippe Kadhel

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  1. Daphné Borja de Mozota
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  2. Philippe Kadhel
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Correspondence to Daphné Borja de Mozota.

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Borja de Mozota, D., Kadhel, P. & Janky, E. Fertility, pregnancy outcomes and deliveries following myomectomy: experience of a French Caribbean University Hospital. Arch Gynecol Obstet 289, 681–686 (2014). https://doi.org/10.1007/s00404-013-3038-y

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  • DOI: https://doi.org/10.1007/s00404-013-3038-y

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