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Chronic hepatitis B virus infection in women is not associated with IVF/ICSI outcomes

Archives of Gynecology and Obstetrics volume 289, pages 213–217 (2014)Cite this article

Abstract

Objective

This study was to evaluate whether chronic HBV (Hepatitis B virus) infection in women is associated with poor performance following IVF/ICSI (in vitro fertilization/intracytoplasmic sperm injection) treatments.

Materials and methods

123 cycles with female chronic HBV infection were compared with 246 cycles with no-infected couples, matched for female age, D3 serum FSH (follicles stimulation hormone) levels, body mass index and assisted reproductive technology approach used (IVF or ICSI), in a ratio of 1:2.

Results

The details in IVF/ICSI cycles, including the dosage of gonadotrophin used, the serum estradiol levels and the endometrial thickness on the day of hCG (human chorionic gonadotrophin) injection, the mean number of oocytes retrieved, and the embryology data, were similar among seropositive and seronegative women. And there was no significant differences in implantation rates and live birth rates between seropositive women group and matched control (30.52 versus 28.34 % per transfer; 42.28 versus 40.65 %).

Conclusions

The results indicated that women with chronic HBV infection is not associated with outcomes of IVF/ICSI treatments.

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Acknowledgments

We would like thank Ghamor-Amegavi Edem Prince for assistance in writings and grammar error correction.

Conflict of interest

The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.

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Affiliations

  1. The Reproductive Medicine Center, The Second Affiliated Hospital of WenZhou Medical University, WenZhou, China

    Hua Chen, Hong-Shan Ge, Jie-Qiang Lv, Xin-Mei Wu, Hai-Tao Xi, Jian-Ying Huang & Chun-Fang Zhu

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  1. Hua Chen
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  2. Hong-Shan Ge
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  7. Chun-Fang Zhu
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Correspondence to Hua Chen.

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Chen, H., Ge, HS., Lv, JQ. et al. Chronic hepatitis B virus infection in women is not associated with IVF/ICSI outcomes. Arch Gynecol Obstet 289, 213–217 (2014). https://doi.org/10.1007/s00404-013-2975-9

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  • DOI: https://doi.org/10.1007/s00404-013-2975-9

Keywords

  • Hepatitis B virus
  • IVF/ICSI
  • Outcomes
  • Pregnancy