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Cervical digital photography for screening of uterine cervix cancer and its precursor lesions in developing countries

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

This study aims to evaluate and to compare the performance of cervical digital photography (CDP) to the visual inspection with acetic acid (VIA) and visual inspection with Lugol’s iodine (VILI) methods for screening the uterine cervix cancer and its precursor lesions in developing countries.

Methods

A cross-sectional study was performed in Brazil. 176 women were evaluated by VIA, VILI, CDP with acetic acid and CDP with Lugol’s iodine. Kappa statistic was used to estimate the interobserver and intermethod agreement. Sensitivity, specificity and diagnostic accuracy of the four methods (VIA, VILI, CDP with acetic acid, CDP with Lugol’s iodine) was calculated.

Results

Interobserver agreement for CDP with acetic acid was K = 0.441 and for CDP with Lugol’s iodine was K = 0.533; intermethod agreement of VIA and CDP with acetic acid, K = 0.559; and of VILI and CDP with Lugol’s iodine, K = 0.507. Sensitivity and specificity of CDP with acetic acid were 84.00 and 95.83 %, and of CDP with Lugol’s iodine were 88.00 and 97.26 %, respectively. The diagnostic accuracy of CDP with acetic acid and CDP with Lugol’s iodine was 92.78 and 94.90 %, respectively.

Conclusion

This was the first study to assess the CDP with Lugol’s iodine performance, which had similar performance to the CDP with acetic acid. CDP is considered a promising method for screening the uterine cervix cancer and its precursor lesions in developing countries.

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Acknowledgments

Financial support: Fundo de Incentivo a Pesquisa (FIPE) do Grupo de Pesquisa e Pós-Graduação (GPPG) do Hospital de Clínicas de Porto Alegre (HCPA). Edison Capp is a scholarship recipient from CNPq and Elise de Castro Hillmann was a scholarship recipient from CAPES.

Conflict of interest

The authors have no conflict of interest.

Author information

Authors and Affiliations

  1. Faculdade de Medicina, Programa de Pós-Graduação em Medicina: Ciências Médicas, Porto Alegre, Brazil

    Elise de Castro Hillmann, Ricardo dos Reis & Edison Capp

  2. Serviço de Ginecologia e Obstetrícia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil

    Ricardo dos Reis, Heleusa Monego, Márcia Appel, Waldemar Augusto Rivoire & Edison Capp

  3. Departamento de Ginecologia e Obstetrícia: Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

    Ricardo dos Reis, Waldemar Augusto Rivoire & Edison Capp

  4. Instituto de Ensino e Pesquisa, Hospital Moinhos de Ventos, Porto Alegre, Brazil

    Luciano Serpa Hammes

  5. Laboratório de Ginecologia e Obstetrícia Molecular, Centro de Pesquisas, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, 90 035-903, Brazil

    Edison Capp

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  1. Elise de Castro Hillmann
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Correspondence to Edison Capp.

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Hillmann, E.C., dos Reis, R., Monego, H. et al. Cervical digital photography for screening of uterine cervix cancer and its precursor lesions in developing countries. Arch Gynecol Obstet 288, 183–189 (2013). https://doi.org/10.1007/s00404-013-2745-8

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  • DOI: https://doi.org/10.1007/s00404-013-2745-8

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