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Chest wall resection and reconstruction for locally advanced primary breast cancer

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

We sought to evaluate clinical and oncologic outcomes of selected patients with locally advanced breast cancer undergoing full thickness chest wall resection (FTCWR) and reconstruction in a multidisciplinary setting.

Patients and methods

Between 2008 and 2010, five women underwent FTCWR followed by chest wall repair for locally advanced primary breast cancer. In all cases, chest wall repair was performed with a Peri-Guard Repair Patch (Synovis, St. Paul, MN, USA). At follow-up (7–12 months) quality of life, respiratory function and oncologic status were assessed.

Results

Successful chest wall resection and repair were achieved in all patients. Plastic reconstruction of post-mastectomy tissue defects was necessary in one case. One patient was treated by breast conserving therapy. Chest ultrasound imaging confirmed absence of adhesions, haematoma or seroma and normal expansion and respiratory movement of the underlying lung in all patients. On follow-up all patients reported good quality of life.

Conclusion

Multidisciplinary surgical approaches to chest wall resection and reconstruction in selected patients with locally advanced primary breast cancer are feasible, safe, associated with short operation time and hospital stay and negligible morbidity.

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References

  1. Hortobagyi GN, Pritchard K, Amadori D, Haidinger R, Hudis CA, Khaled H, Liu MC, Martin M, Namer M, O’Shaughnessy JA, Shen ZZ, Albain KS, ABREAST Investigators (2005) The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer 6:391–401

    Article  PubMed  Google Scholar 

  2. Harris JR, Lippman ME, Morrow M, Osborne CK (2010) Diseases of the breast, 4th edn. Lippincott Williams and Wilkins, Philadelphia, p 492

    Google Scholar 

  3. Kroll SS, Schusterman MA, Larson DL, Fender A (1990) Long time survival after chest wall reconstruction with musculocutaneous flaps. Plast Reconstr Surg 86:697–701

    Article  PubMed  CAS  Google Scholar 

  4. Downey RJ, Rusch V, Hsu FI, Leon L, Venkatraman E, Linehan D, Bains M, van Zee K, Korst R, Ginsberg R (2000) Chest wall resection for locally recurrent breast cancer: is it worthwhile? J Thorac Cardiovasc Surg 119:420–428

    Article  PubMed  CAS  Google Scholar 

  5. Wiegmann B, Zardo P, Dickgreber N, Länger F, Fegbeutel C, Haverich A, Fischer S (2010) Biological materials in chest wall reconstruction: initial experience with the peri-guard repair patch. Eur J Cardiothorac Surg 37:602–605

    Article  PubMed  Google Scholar 

  6. Hathaway CL, Rand RP, Moe R, Marchioro T (1994) Salvage surgery for locally advanced breast cancer and locally recurrent breast cancer. Arch Surg 129:582–587

    Article  PubMed  CAS  Google Scholar 

  7. Veronesi G, Scanagatta P, Goldhirsch A, Rietjens M, Colleoni M, Pelosi G, Spaggiari L (2007) Results of chest wall resection for recurrent or locally advanced breast malignancies. Breast 16:297–302

    Article  PubMed  Google Scholar 

  8. Faneyte IF, Rutgers EJ, Zoetmulder FA (1997) Chest wall resection in the treatment of locally recurrent breast carcinoma: indications and outcome for 44 patients. Cancer 80:886–891

    Article  PubMed  CAS  Google Scholar 

  9. Santillan AA, Kiluk JV, Cox JM, Meade TL, Allred N, Ramos D, King J, Cox CE (2008) Outcomes of locoregional recurrence after surgical chest wall resection and reconstruction for breast cancer. Ann Surg Oncol 15:1322–1329

    Article  PubMed  Google Scholar 

  10. Chen KN, Yu P (2006) Significance of multidisciplinary surgery in chest wall resection and reconstruction for selected patients with breast cancer. Zhonghua Zhong Liu Za Zhi 28:856–859

    PubMed  Google Scholar 

  11. Qin X, Tang H, Xu Z, Zhao X, Sun Y, Gong Z, Duan L (2008) Chest wall reconstruction with two types of biodegradable polymer prostheses in dogs. Eur J Cardiothorac Surg 34:870–874

    Article  PubMed  Google Scholar 

  12. Weyant MJ, Bains MS, Venkatraman E, Downey RJ, Park BJ, Flores RM, Rizk N, Rusch VW (2006) Results of chest wall resection and reconstruction with and without rigid prosthesis. Ann Thorac Surg 81:279–285

    Article  PubMed  Google Scholar 

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Conflict of interest

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    Ursula Hille & Philipp Soergel

  2. Department of Thoracic Surgery, Klinikum Ibbenbüren, Große Str. 41, 49477, Ibbenbüren, Germany

    Patrick Zardo & Stefan Fischer

  3. Department of Radiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    Stefanie Pertschy

  4. Department of Plastic Surgery, Malteser Hospital Bonn, Von-Hompesch-Straße 1, 53123, Bonn, Germany

    Kai Busch

Authors
  1. Ursula Hille
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  2. Philipp Soergel
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  3. Patrick Zardo
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  4. Stefanie Pertschy
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  5. Kai Busch
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  6. Stefan Fischer
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Corresponding author

Correspondence to Philipp Soergel.

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Hille, U., Soergel, P., Zardo, P. et al. Chest wall resection and reconstruction for locally advanced primary breast cancer. Arch Gynecol Obstet 287, 1205–1209 (2013). https://doi.org/10.1007/s00404-012-2682-y

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  • DOI: https://doi.org/10.1007/s00404-012-2682-y

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