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Early embryonic morphology sonographically assessed and its correlation with yolk sac in missed abortion

  • Reproductive Medicine
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Abstract

Purpose

To provide additional information about embryo morphology sonographic assessment and its correlation with yolk sac.

Methods

A systematic study in 200 consecutive cases of missed abortion <10 weeks diagnosed by transvaginal ultrasound.

Results

In 104 gestations of embryos with morphological abnormalities, 88 (84.6 %) were at least 1 week smaller than expected for gestational age and 16 (15.4 %) were the expected size. From 32 normal morphologic embryos, 7 (21.9 %) were at least 1 week smaller than expected for gestational age, and 25 (78.1 %) were the expected size (p < 0.005). Normal morphologic embryos are linked more frequently with normal yolk sac (62.5 %). Findings in anembryonic gestations (GD1) included an absent yolk sac (46.9 %) and a cystic yolk sac (25 %). Likewise, findings in GD2-3 embryos included more frequently a cystic yolk sac (42.9 %) and an absent yolk sac (32.5 %). GD4 embryos are associated with an echogenic yolk sac (40 %), a relatively small-hypoplastic- (40 %) and a relatively large-cystic- (20 %). In DI embryos, yolk sac appears cystic (62.5 %) or echogenic (37.5 %).

Conclusions

Our study proves the correlation between morphology of conceptuses and yolk sac appearance in cases of missed abortion.

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We declare that we have no conflict of interest.

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Correspondence to Juan Mozas.

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Salamanca, A., Fernández-Salmerón, P., Beltrán, E. et al. Early embryonic morphology sonographically assessed and its correlation with yolk sac in missed abortion. Arch Gynecol Obstet 287, 139–142 (2013). https://doi.org/10.1007/s00404-012-2499-8

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  • DOI: https://doi.org/10.1007/s00404-012-2499-8

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