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MR imaging evaluation of fibroid clearance following open myomectomy for massive/multiple symptomatic fibroids

  • General Gynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the technical success of total fibroid clearance at open myomectomy for massive and/or multiple symptomatic fibroids using MR imaging (MRI) as the imaging modality.

Methods

The study group comprised 27 women [mean age 37.4 ± 6.9 years (range 27–53)] who underwent open myomectomy for the treatment of massive/multiple symptomatic fibroids at our institution between January 2009 and April 2010. Myomectomy was performed with the intention of achieving complete fibroid clearance. Pre- and postmyomectomy MRI was performed to assess changes in uterine volume and fibroid burden. Periprocedural data (including blood loss and complications) and relief of clinical symptoms at follow-up were also recorded.

Results

The mean time to MRI and clinical follow-up was 10 months (range 6–15 months). The mean uterine volume premyomectomy was 795 ± 580 cc and postmyomectomy was 123 ± 70 cc (p < 0.001). The mean percentage reduction in uterine volume was 80.3 % (range 43.0–98.1 %). Of the 10/27 (37.0 %) women with residual fibroids at follow-up: 7 patients had fibroids measuring up to 1 cc in volume, 3 patients had fibroids measuring up to 6 cc. Postoperative adnexal seromas were observed in 6/27 (22.2 %) patients. The clinical success rates of myomectomy amongst the 22/27 (81 %) responders were: 73 % for menorrhagia, 64 % for pain, and 36–64 % for mass-related symptoms.

Conclusions

Using MRI, we have confirmed that open myomectomy can achieve total or near-total fibroid clearance in the majority of patients with massive and/or multiple fibroids.

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References

  1. van der Kooij SM, Hehenkamp WJ, Volkers NA et al (2010) Uterine artery embolization vs hysterectomy in the treatment of symptomatic uterine fibroids: 5-year outcome from the randomized EMMY trial. Am J Obstet Gynecol 203:105.e1-13

    PubMed  Google Scholar 

  2. Smeets AJ, Nijenhuis RJ, van Rooij WJ et al (2010) Uterine artery embolization in patients with a large fibroid burden: long-term clinical and MR follow-up. Cardiovasc Intervent Radiol 33:943–948

    Article  PubMed  Google Scholar 

  3. Berkane N, Moutafoff-Borie C (2010) Impact of previous uterine artery embolization on fertility. Curr Opin Obstet Gynecol 22:242–247

    Article  PubMed  Google Scholar 

  4. Taylor A, Sharma M, Tsirkas P et al (2005) Surgical and radiological management of uterine fibroids—a UK survey of current consultant practice. Acta Obstet Gynecol Scand 84:478–482

    PubMed  Google Scholar 

  5. Tulandi T, Murray C, Guralnick M (1993) Adhesion formation and reproductive outcome after myomectomy and second look laparoscopy. Obstet Gynecol 82:213–215

    PubMed  CAS  Google Scholar 

  6. Thompson LB, Reed SD, McCrummen BK et al (2006) Leiomyoma characteristics and risk of subsequent surgery after myomectomy. Int J Gynaecol Obstet 95:138–143

    Article  PubMed  CAS  Google Scholar 

  7. Tsuji S, Takahashi K, Imaoka I et al (2006) MRI evaluation of the uterine structure after myomectomy. Gynecol Obstet Invest 61:106–110

    Article  PubMed  Google Scholar 

  8. Manyonda IT, Bratby M, Horst JS et al (2011) Uterine artery embolization versus myomectomy: impact on quality of life-results of the FUME (Fibroids of the Uterus: Myomectomy versus Embolization) trial. Cardiovasc Intervent Radiol Jul 20 [Epub ahead of print]

  9. Peddada SD, Laughlin SK, Miner K et al (2008) Growth of uterine leiomyomata among premenopausal black and white women. Proc Natl Acad Sci USA 105:19887–19892

    Article  PubMed  CAS  Google Scholar 

  10. Mukhopadhaya N, De Silva C, Manyonda IT (2008) Conventional myomectomy. Best Pract Res Clin Obstet Gynaecol 22:677–705

    Article  PubMed  Google Scholar 

  11. Byrne H, Miskry T, Gomez CM (2009) Using vasopressin for myomectomy. Obstet Gynecol 114:169–170

    PubMed  Google Scholar 

  12. Parthipun AA, Taylor J, Manyonda I et al (2010) Does size really matter? Analysis of the effect of large fibroids and uterine volumes on complication rates of uterine artery embolisation. Cardiovasc Intervent Radiol 33:955–959

    Article  PubMed  CAS  Google Scholar 

  13. Razavi MK, Hwang G, Jahed A et al (2003) Abdominal myomectomy versus uterine fibroid embolization in the treatment of symptomatic uterine leiomyomas. Am J Roentgenol 180:1571–1575

    Google Scholar 

  14. Schüring AN, Garcia-Rocha GJ, Schlösser HW et al (2010) Perioperative complications in conventional and microsurgical abdominal myomectomy. Arch Gynecol Obstet Aug 1 [Epub ahead of print]

  15. LaMorte AI, Lalwani S, Diamond MP (1993) Morbidity associated with abdominal myomectomy. Obstet Gynecol 82:897–900

    PubMed  CAS  Google Scholar 

  16. Hutchins FL Jr (1995) Abdominal myomectomy as a treatment for symptomatic uterine fibroids. Obstet Gynecol Clin North Am 22:781–789

    PubMed  Google Scholar 

  17. Fauconnier A, Chapron C, Babaki-Fard K, Dubuisson JB (2000) Recurrence of leiomyomata after myomectomy. Hum Reprod Update 6:595–602

    Article  PubMed  CAS  Google Scholar 

  18. Subramanian S, Clark MA, Isaacson K (2001) Outcome and resource use associated with myomectomy. Obstet Gynecol 98:583–587

    Article  PubMed  CAS  Google Scholar 

  19. Iverson RE Jr, Chelmow D, Strohbehn K et al (1996) Relative morbidity of abdominal hysterectomy and myomectomy for management of uterine leiomyomas. Obstet Gynecol 88:415–419

    Article  PubMed  Google Scholar 

  20. Farhi J, Ashkenazi J, Feldberg D et al (1995) Effect of uterine leiomyomata on the results of in vitro fertilization treatment. Hum Reprod 10:2576–2578

    Article  PubMed  CAS  Google Scholar 

  21. Sinha R, Hegde A, Mahajan C et al (2008) Laparoscopic myomectomy: do size, number, and location of the myomas form limiting factors for laparoscopic myomectomy? J Minim Invasive Gynecol 15:292–300

    Article  PubMed  Google Scholar 

  22. Tinelli A, Malvasi A, Hudelist G et al (2010) Laparoscopic intracapsular myomectomy: comparison of single versus multiple fibroids removal. An institutional experience. J Laparoendosc Adv Surg Tech A 20:705–771

    Article  PubMed  Google Scholar 

  23. Kirby JM, Burrows D, Haider E et al (2011) Utility of MRI before and after uterine fibroid embolization: why to do it and what to look for. Cardiovasc Intervent Radiol 34:705–716

    Article  PubMed  Google Scholar 

  24. Landi S, Zaccoletti R, Ferrari L et al (2001) Laparoscopic myomectomy: technique, complications, and ultrasound scan evaluations. J Am Assoc Gynecol Laparosc 8:231–240

    Article  PubMed  CAS  Google Scholar 

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We declare that we have no conflicts of interest.

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Correspondence to Nevin T. Wijesekera.

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Wijesekera, N.T., Mauri, G., Gupta, S. et al. MR imaging evaluation of fibroid clearance following open myomectomy for massive/multiple symptomatic fibroids. Arch Gynecol Obstet 286, 1165–1171 (2012). https://doi.org/10.1007/s00404-012-2404-5

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  • DOI: https://doi.org/10.1007/s00404-012-2404-5

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