Bee-honey and yogurt: a novel mixture for treating patients with vulvovaginal candidiasis during pregnancy
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To evaluate the clinical and mycological cure rates of a novel mixture consisting of Bee-honey and yogurt compared to local antifungal agents for treating patients with vulvo-vaginal candidiasis (VVC) during pregnancy.
Materials and methods
This is a prospective comparative study which included 129 patients with VVC during pregnancy. The participants were allocated into study group (n = 82) who received a mixture of Bee-honey and yogurt vaginally and control group (n = 47) who received local anti-fungal agents. The Chi-square test was used to evaluate the clinical and mycological cure rates and the side-effects of both modes of therapy.
The clinical cure rate was significantly higher in the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the control than the study group (91.5 vs. 76.9%, respectively). Both types of therapy were favorably tolerated by most of the patients. Side effects were reported only in 24.3 and 29.7% of patients in group I and II, respectively (p < 0.05).
The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an alternative to antifungal agents especially in patients with VVC during pregnancy.
KeywordsBee-honey Yogurt Antifungal agents Vulvo-vaginal candidiasis
Conflict of interest
We declare that we have no conflict of interest.
- 14.Molan PC (1992) The antibacterial activity of honey: 2. Variation in the potency of the antibacterial activity. Bee World 73:59–76Google Scholar
- 16.Sissons CH, Anderson SA, Molan PC (2004) Suppression of C. albicans in plaque microcosms by manuka honey. In: IADR/AADR/CADR 82nd General Session in Honolulu, Hawai, 2004Google Scholar
- 20.Osset J, Garcia E, Bartolome R, Andreu A (2001) Role of Lactobacillus as protector against vaginal candidiasis. Med Clin 117(8):285–288Google Scholar
- 21.Williams A (2002) Yogurt: still a favorite for vaginal candidiasis? J Nat Med Assoc 94(4):A10Google Scholar
- 22.Holmberg K, Meyer RD (1989) Diagnosis and therapy of systemic fungal infections. Raven Press, New YorkGoogle Scholar