Archives of Gynecology and Obstetrics

, Volume 286, Issue 1, pp 109–114 | Cite as

Bee-honey and yogurt: a novel mixture for treating patients with vulvovaginal candidiasis during pregnancy

  • Allam M. AbdelmonemEmail author
  • Salah M. Rasheed
  • Abeer Sh Mohamed
General Gynecology



To evaluate the clinical and mycological cure rates of a novel mixture consisting of Bee-honey and yogurt compared to local antifungal agents for treating patients with vulvo-vaginal candidiasis (VVC) during pregnancy.

Materials and methods

This is a prospective comparative study which included 129 patients with VVC during pregnancy. The participants were allocated into study group (n = 82) who received a mixture of Bee-honey and yogurt vaginally and control group (n = 47) who received local anti-fungal agents. The Chi-square test was used to evaluate the clinical and mycological cure rates and the side-effects of both modes of therapy.


The clinical cure rate was significantly higher in the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the control than the study group (91.5 vs. 76.9%, respectively). Both types of therapy were favorably tolerated by most of the patients. Side effects were reported only in 24.3 and 29.7% of patients in group I and II, respectively (p < 0.05).


The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an alternative to antifungal agents especially in patients with VVC during pregnancy.


Bee-honey Yogurt Antifungal agents Vulvo-vaginal candidiasis 


Conflict of interest

We declare that we have no conflict of interest.


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Allam M. Abdelmonem
    • 1
    Email author
  • Salah M. Rasheed
    • 1
  • Abeer Sh Mohamed
    • 2
  1. 1.Department of Obstetrics and Gynecology, Sohag Faculty of MedicineSohag UniversitySohagEgypt
  2. 2.Department of Medical Microbiology and Immunology, Sohag Faculty of MedicineSohag UniversitySohagEgypt

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