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Induction of labor in prolonged pregnancy with unfavorable cervix: comparison of sequential intracervical Foley catheter–intravaginal misoprostol and intravaginal misoprostol alone

Archives of Gynecology and Obstetrics volume 285, pages 967–971 (2012)Cite this article

Abstract

Purpose

To compare the outcome of induced labor at term using sequential intracervical Foley catheter with intravaginal misoprostol versus intravaginal misoprostol alone.

Methods

A prospective matched case control study among parturient with prolonged pregnancy and unfavorable cervix at a tertiary hospital in Nigeria.

Results

The study population was 100 with a mean age of 29.46 ± 3.88 years. Parturient with prior cervical priming using intracervical Foley catheter had significantly lower oxytocin augmentation of uterine contractions in labor (44 vs. 64%, P = 0.045), shorter mean insertion to active phase labor duration (233 ± 98 vs. 354 ± 154 min, P = 0.0001), shorter insertion to delivery interval (514 ± 175 vs. 627 ± 268, P = 0.014), more vaginal delivery <12 h (92.5 vs. 60%, P = 0.001) and less delivery by caesarean section (20 vs. 40%, P = 0.029).

Conclusions

The sequential combination of intracervical Foley catheter and intravaginal misoprostol for cervical ripening and induction of labor appears to be a safe and more effective method compared to intravaginal misoprostol in parturient at term with unfavorable cervices.

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Conflict of interest

The authors certify that no actual or potential conflict of interest in relation to this article exists.

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Affiliations

  1. Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria

    A. Babatunde Ande, C. Michael Ezeanochie & N. Biodun Olagbuji

  2. Department of Obstetrics and Gynaecology, College of Health Sciences, University of Benin, Benin City, Edo State, Nigeria

    A. Babatunde Ande

Authors
  1. A. Babatunde Ande
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  2. C. Michael Ezeanochie
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  3. N. Biodun Olagbuji
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Correspondence to A. Babatunde Ande.

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Ande, A.B., Ezeanochie, C.M. & Olagbuji, N.B. Induction of labor in prolonged pregnancy with unfavorable cervix: comparison of sequential intracervical Foley catheter–intravaginal misoprostol and intravaginal misoprostol alone. Arch Gynecol Obstet 285, 967–971 (2012). https://doi.org/10.1007/s00404-011-2094-4

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  • DOI: https://doi.org/10.1007/s00404-011-2094-4

Keywords

  • Induction of labor
  • Prolonged pregnancy
  • Foley catheter
  • Misoprostol