Advertisement

Archives of Gynecology and Obstetrics

, Volume 284, Issue 2, pp 513–516 | Cite as

A singular observation of a giant benign Brenner tumor of the ovary

  • Silvia RuggieroEmail author
  • Valter Ripetti
  • Antonella Bianchi
  • Vincenzo La Vaccara
  • Rossana Alloni
  • Roberto Coppola
Short Communication

Abstract

Introduction

Brenner tumors are rare transitional cell tumors of the ovary. They are usually benign neoplasms, of solid or solid-cystic structure and small size. We describe the case of a benign, predominantly cystic Brenner tumor measuring 39 cm in diameter.

Case report

A 62-year-old woman presented to the outpatient visit complaining about vague abdominal symptoms such as constipation and meteorism. Ultrasonography and CT scan showed the presence of a voluminous cystic mass, with fluid content, displacing other intra-abdominal organs. The patient underwent elective surgical excision, and there were no complications. Definitive pathological examination showed a metaplastic benign Brenner tumor.

Conclusion

The largest benign Brenner tumors reported in literature have been up to 30 cm in size, and greater size has been thought to be a predictor of malignancy. We have seen, however, that it is possible for larger lesions of this type to have a completely benign behavior; consequently, a benign nature should not be excluded even in the event of a large ovarian lesion.

Keywords

Ovarian neoplasms Brenner tumor Giant Ovarian cyst 

Notes

Conflict of interest

We declare that we have no conflict of interest.

References

  1. 1.
    Tavassoli FA, Devilee P (2003) Pathology and genetics of tumours of the breast and female genital organs. IARC Press, LyonGoogle Scholar
  2. 2.
    Heye S, Bielen D, Vanbeckevoort D (2005) Left ovarian Brenner tumor. JBR-BTR 88(5):245–246PubMedGoogle Scholar
  3. 3.
    Silverberg SG (1971) Brenner tumor of the ovary: a clinicopathologic study of 60 tumors in 54 women. Cancer 28(3):588–596PubMedCrossRefGoogle Scholar
  4. 4.
    Cuatrecasas M, Catasus L, Palacios J, Prat J (2009) Transitional cell tumors of the ovary: a comparative clinicopathologic, immunohistochemical, and molecular genetic analysis of Brenner tumors and transitional cell carcinomas. Am J Surg Pathol 33(4):556–567PubMedCrossRefGoogle Scholar
  5. 5.
    Green GE, Mortele KJ, Glickman JN, Benson CB (2006) Brenner tumors of the ovary: sonographic and computed tomographic imaging features. J Ultrasound Med 25(10):1245–1251PubMedGoogle Scholar
  6. 6.
    Kourda N, Elloumi H, Chérif K, Ben Jilani S, Zermani R (2008) Proliferating Brenner tumor: case report. Gynecol Obstet Fertil 36(3):292–295PubMedCrossRefGoogle Scholar
  7. 7.
    Balasa RW, Adcock LL, Prem KA, Dehner LP (1977) The Brenner tumor: a clinicopathologic review. Obstet Gynecol 50(1):120–128PubMedGoogle Scholar
  8. 8.
    Roth LM, Dallenbach-Hellweg G, Czernobilsky B (1985) Ovarian Brenner tumors I. Metaplastic, proliferating, and of low malignant potential. Cancer 56(3):582–591PubMedCrossRefGoogle Scholar
  9. 9.
    Roth LM, Czernobilsky B (1985) Ovarian Brenner tumors II. Malignant. Cancer 56(3):592–601PubMedCrossRefGoogle Scholar
  10. 10.
    Mülayim B, Gürakan H, Mülayim S, Ayidin O, Akkaya H (2006) Unaware of a giant serous cyst adenoma: a case report. Arch Gynecol Obstet 273(6):381–383PubMedCrossRefGoogle Scholar
  11. 11.
    Baker PM, Young RH (2003) Brenner tumor of the ovary with striking microcystic change. Int J Gynecol Pathol 22(2):185–188PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Silvia Ruggiero
    • 1
    Email author
  • Valter Ripetti
    • 1
  • Antonella Bianchi
    • 1
    • 2
  • Vincenzo La Vaccara
    • 1
  • Rossana Alloni
    • 1
  • Roberto Coppola
    • 1
  1. 1.Department of SurgeryUniversity Campus Bio-Medico of RomeRomeItaly
  2. 2.Department of PathologyUniversity Campus Bio-Medico of RomeRomeItaly

Personalised recommendations