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Is the yolk sac a new marker for chromosomal abnormalities in early pregnancy?

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Abstract

Introduction

Abnormal yolk sac size is associated with fetal miscarriage. This is a case report of two pregnancies with abnormal yolk sacs.

Materials and methods

In one case, a twofold sac was found; in the other case, the yolk sac was not of spherical form.

Conclusion

Currently available publications demonstrate a correlation between abnormal yolk sac size and miscarriage. However, in both cases a trisomy was confirmed. It should therefore be discussed whether form and size of the yolk sac could be a marker for chromosomal abnormalities of the fetus.

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Conflict of interest

The authors declare that there are no conflicts of interests.

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Authors and Affiliations

  1. Bahnhofstraße 4, 38300, Wolfenbüttel, Germany

    Peter Schmidt

  2. Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany

    Cindy Hörmansdörfer, Stephan Bosselmann, Michael Elsässer & Alexander Scharf

Authors
  1. Peter Schmidt
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  2. Cindy Hörmansdörfer
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  3. Stephan Bosselmann
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  4. Michael Elsässer
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  5. Alexander Scharf
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Correspondence to Peter Schmidt.

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Schmidt, P., Hörmansdörfer, C., Bosselmann, S. et al. Is the yolk sac a new marker for chromosomal abnormalities in early pregnancy?. Arch Gynecol Obstet 283 (Suppl 1), 23–26 (2011). https://doi.org/10.1007/s00404-010-1696-6

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  • DOI: https://doi.org/10.1007/s00404-010-1696-6

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