Archives of Gynecology and Obstetrics

, Volume 284, Issue 2, pp 337–341 | Cite as

Is induced labour in the nullipara associated with more maternal and perinatal morbidity?

  • Dan Selo-OjemeEmail author
  • Cathy Rogers
  • Ashok Mohanty
  • Naseem Zaidi
  • Rose Villar
  • Panicos Shangaris
Materno-Fetal Medicine



To ascertain any differences in foetomaternal outcomes in induced and spontaneous labour among nulliparous women delivering at term.


A retrospective matched cohort study consisting of 403 nulliparous women induced at ≥292 days and 806 nulliparous women with spontaneous labour at 285–291 days.


Compared to those in spontaneous labour, women who had induction of labour were three times more likely to have a caesarean delivery (OR 3.1, 95% CI 2.4–4.1; P < 0.001). Women who had induction of labour were 2.2 times more likely to have oxytocin augmentation (OR 2.2, 95% CI 1.7–2.8; P < 0.001), 3.6 times more likely to have epidural anaesthesia (OR 3.6, 95% CI 2.8–4.6; P < 0.001), 1.7 times more likely to have uterine hyperstimulation (OR 1.7, 95% CI 1.1–2.6), 2 times more likely to have a suspicious foetal heart rate trace (OR 2.0, 95% CI 1.5–2.6), 4.1 times more likely to have blood loss over 500 ml (OR 4.1, 95% CI 2.95.5; P < 0.001), and 2.9 times more likely to stay in hospital beyond 5 days (OR 2.9, 95% CI 1.5–5.6; P < 0.001). Babies born to mothers who had induction of labour were significantly more likely to have an Apgar score of <5 at 5 min and an arterial cord pH of <7.0.


Compared to those with spontaneous labour, nulliparous women with induced labours are more likely to have uterine hyperstimulation, caesarean delivery, and babies with low Apgar scores. Nulliparous women should be made aware of this, as well as potential risks of expectant management during counseling.


Induction of labour Spontaneous labour Caesarean section Pregnancy complication Neonatal outcome 


Conflict of interest

There are no conflicts of interest to disclose.


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Dan Selo-Ojeme
    • 1
    Email author
  • Cathy Rogers
    • 1
  • Ashok Mohanty
    • 1
  • Naseem Zaidi
    • 1
  • Rose Villar
    • 1
  • Panicos Shangaris
    • 1
  1. 1.Department of Obstetrics and Gynaecology, Women and Children’s Directorate, Barnet and Chase Farm Hospitals NHS TrustChase Farm HospitalEnfieldUK

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