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Perinatal outcomes in condyloma acuminata pregnancies

  • Materno-fetal Medicine
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Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

To investigate pregnancy outcome in patients with condyloma acuminata.

Methods

A retrospective cohort study comparing pregnancy outcome of women with and without condyloma acuminata was performed. A sub-group analysis was performed between patients with localized disease (n = 40), extended disease (n = 25) and no condyloma acuminata (n = 227,202).

Results

Using a multivariate logistic regression model, condyloma acuminata was significantly associated with cesarean delivery (OR = 3.4; 95% CI 1.9–5.8; P < 0.001), nulliparity (OR = 4.8; 95% CI 2.6–9.0; P < 0.001), and Jewish ethnicity (vs. Bedouin Arabs; OR = 2.3; 95% CI 1.3–4.1; P < 0.001). A significant linear association was found between the three subgroup (extended condyloma, localized condyloma and no condyloma) and cesarean delivery (40.0% in the extended disease vs. 32.5% in the localized disease vs. 13.0% in the comparison group P < 0.001). No significant differences were noted between the groups in terms of perinatal outcomes, such as low Apgar score (<7) at 1 min (4.2 vs. 1.6%; P = 0.298) and 5 min (0.6 vs. 0.0% P = 0.534) and perinatal mortality (1.4 vs. 1.5% P = 0.912).

Conclusions

Women with condyloma acuminata are at an increased risk for cesarean delivery, while the risk for cesarean delivery is higher for pregnancies with extended when compared with localized disease. Nevertheless, condyloma acuminata is not associated with adverse perinatal outcome.

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Conflict of interest statement

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Authors and Affiliations

  1. Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheba, Israel

    Eyal Cohen

  2. Epidemiology and Health Services Evaluation, Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheba, Israel

    Amalia Levy

  3. Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University, Medical Center, Ben Gurion University of the Negev, P.O. Box 151, Beersheba, Israel

    Gershon Holcberg, Arnon Wiznitzer, Moshe Mazor & Eyal Sheiner

Authors
  1. Eyal Cohen
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  2. Amalia Levy
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  3. Gershon Holcberg
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  4. Arnon Wiznitzer
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  5. Moshe Mazor
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  6. Eyal Sheiner
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Corresponding author

Correspondence to Eyal Sheiner.

Additional information

Performed in part of Eyal Cohen’s MD requirements.

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Cohen, E., Levy, A., Holcberg, G. et al. Perinatal outcomes in condyloma acuminata pregnancies. Arch Gynecol Obstet 283, 1269–1273 (2011). https://doi.org/10.1007/s00404-010-1558-2

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  • DOI: https://doi.org/10.1007/s00404-010-1558-2

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