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Region-based diagnostic performance of multidetector CT for detecting peritoneal seeding in ovarian cancer patients

Abstract

Purpose

To determine the accuracy of multi-detector CT (MDCT) compared with the surgical findings, such as peritoneal seeding and metastatic lymph nodes, in ovarian cancer patients.

Methods

Fifty-seven FIGO stage IA–IV ovarian cancer patients, who underwent MDCT before primary surgery, were included in this study. Two radiologists evaluated the following imaging findings in consensus: the presence of nodular, plaque-like or infiltrative soft-tissue lesions in peritoneal fat or on the serosal surface; presence of ascites; parietal peritoneal thickening or enhancement; and small bowel wall thickening or distortion. We also evaluated the presence of lymph node metastases. To allow region-specific comparisons, the peritoneal cavity was divided into 13 regions and retroperitoneal lymph nodes were divided into 3 regions. Descriptive statistical data were thus obtained.

Results

The MDCT sensitivity, specificity, positive predictive values, and negative predictive values were 45, 72, 46, and 72%, respectively, for detecting peritoneal seeding and 21, 90, 52, and 69%, respectively, for detecting lymph node metastasis.

Conclusions

MDCT is moderately accurate for detecting peritoneal metastasis and lymph node metastasis in ovarian cancer patients.

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Acknowledgments

The authors would like to thank all of the anesthesiologists, surgeons, and surgery nurses at the Center for Uterine Cancer for their invaluable help, patience, and active participation in this study. The authors also would like to thank Wha-Eun Lee and Soo Yeon Jung, research nurses at the National Cancer Center, Korea, for their efforts in gathering and organizing the data and Myungeun Lim (Jessica Lim) for drawing the illustration (Fig. 1). This work was supported by Grants (1010111-1) offered by the National Cancer Center.

Conflict of interest statement

The authors have no conflict of interest to declare.

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Correspondence to Sang-Yoon Park.

Additional information

H. J. Choi and M. C. Lim contributed equally to this work.

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Choi, H.J., Lim, M.C., Bae, J. et al. Region-based diagnostic performance of multidetector CT for detecting peritoneal seeding in ovarian cancer patients. Arch Gynecol Obstet 283, 353–360 (2011). https://doi.org/10.1007/s00404-010-1442-0

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  • DOI: https://doi.org/10.1007/s00404-010-1442-0

Keywords

  • Ovarian cancer
  • Peritoneal seeding
  • Multi-detector computed tomography