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Periodic urinary protein creatinine ratio for predicting significant proteinuria in preeclampsia in different alternatives: time effectiveness analysis

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Abstract

Preeclampsia is a big problem in obstetrics. The diagnosis relies mainly on the detection of both hypertension and proteinuria. The gold standard for the determination of proteinuria is 24 h urinary protein creatinine ratio; however, this approach is inconvenient and it is a considerable time consuming process that might bring a delayed diagnosis which might result in delayed treatment. Although spot urine measurement can be done, it has very poor prediction. The use of periodic urinary protein creatinine ratio is proposed as a possible alternative to solve this problem. Here, the author tries to perform a time effectiveness analysis for reported models on periodical urinary protein creatinine ratio for predicting significant proteinuria in preeclampsia. Data from previously published reports on this topic are used for further analysis. It seems that the alternative, 4 h, gives the most effectiveness in the shortest period of turnaround time. Hence, this alternative is recommended for screening proteinuria.

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The author declares that there is no conflict of interest in this work.

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  1. Wiwanitkit House, Bangkhae, Bangkok, 10160, Thailand

    Viroj Wiwanitkit

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  1. Viroj Wiwanitkit
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Correspondence to Viroj Wiwanitkit.

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Wiwanitkit, V. Periodic urinary protein creatinine ratio for predicting significant proteinuria in preeclampsia in different alternatives: time effectiveness analysis. Arch Gynecol Obstet 281, 571–573 (2010). https://doi.org/10.1007/s00404-009-1167-0

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  • DOI: https://doi.org/10.1007/s00404-009-1167-0

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