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Adenocarcinoma arising from the respiratory ciliated epithelium in a benign cystic teratoma of the ovary

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Abstract

Benign cystic teratoma of the ovary (BCTO) is the most common benign ovarian tumor, accounting for 15–20% of all ovarian tumors. It is usually diagnosed in the third and fourth decades of life. Malignant transformation is rare, occurring in approximately 1–2% of reported cases, with squamous cell carcinoma being the most common form. Adenocarcinoma arising from mature cystic teratoma is extremely rare. We present the patient with a BCTO, where a malignant transformation of respiratory ciliated epithelium resulted in well differentiated adenocarcinoma. Although respiratory epithelium is often found in BCTOs, adenocarcinoma arising from this cell type is uncommon. To our knowledge, this is the fourth reported case of adenocarcinoma arising from the respiratory epithelium of a BCTO.

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Authors and Affiliations

  1. Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, 111 Jungbalsan-ro, Ilsandong-gu, Gyeonggi-do, Goyang-si, 410-769, Republic of Korea

    Yong Jung Song

  2. Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, 75 Nowon-gil (215-4 Gongneung-dong), Nowon-gu, Seoul, 139-706, Republic of Korea

    Sang Young Ryu, Suck Chul Choi, Eui Don Lee & Kyung Hee Lee

  3. Department of Pathology, Korea Cancer Center Hospital, Seoul, Republic of Korea

    Soo Youn Cho

Authors
  1. Yong Jung Song
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  2. Sang Young Ryu
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  3. Suck Chul Choi
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  4. Eui Don Lee
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  5. Kyung Hee Lee
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Correspondence to Eui Don Lee.

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Song, Y.J., Ryu, S.Y., Choi, S.C. et al. Adenocarcinoma arising from the respiratory ciliated epithelium in a benign cystic teratoma of the ovary. Arch Gynecol Obstet 280, 659–662 (2009). https://doi.org/10.1007/s00404-009-0978-3

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  • DOI: https://doi.org/10.1007/s00404-009-0978-3

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