Abstract
Objective
To describe the experiences in diagnostic amniocentesis in twin pregnancies.
Methods
The computerized database and medical records of pregnant women attending Maternal Fetal Medicine Unit of the hospital for diagnostic amniocentesis at 16–20 weeks gestation between January 1992 and December 2006 were retrospectively reviewed.
Results
During 15 years of experience, 7,890 amniocenteses at 16–20 weeks gestation were performed for prenatal diagnosis, including 174 procedures in 87 twin pregnancies. The mean gestational age at the time of amniocentesis was 17.13 ± 3.35 weeks. Preterm birth rate defined as the delivery before 36 gestational weeks was 36.24%. The total fetal loss rate was 5.17%, however, the procedure related fetal loss within 2 weeks after the procedure was 1.15%.
Conclusion
Based on our limited data and previous studies, we can counsel patients undergoing twin amniocentesis at mid-trimester that the fetal loss rate may be slightly higher than that of singleton amniocentesis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kogan MD, Alexander GR, Kotelchuck M, MacDorman MF, Buekens P, Martin JA et al (2000) Trends in twin birth outcomes and prenatal care utilization in the United States, 1981–1997. JAMA 284(3):335–341. doi:10.1001/jama.284.3.335
Weisz B, Rodeck CH (2005) Invasive diagnostic procedures in twin pregnancies. Prenat Diagn 25(9):751–758. doi:10.1002/pd.1263
Appelman Z, Furman B (2005) Invasive genetic diagnosis in multiple pregnancies. Obstet Gynecol Clin North Am 32(1):97–103, ix. doi:10.1016/j.ogc.2004.10.003
Ghidini A, Lynch L, Hicks C, Alvarez M, Lockwood CJ (1993) The risk of second-trimester amniocentesis in twin gestations: a case-control study. Am J Obstet Gynecol 169(4):1013–1016
Yukobowich E, Anteby EY, Cohen SM, Lavy Y, Granat M, Yaget S (2001) Risk of fetal loss in twin pregnancies undergoing second trimester amniocentesis (1). Obstet Gynecol 98(2):231–234. doi:10.1016/S0029-7844(01)01416-8
Pruggmayer MR, Jahoda MG, Van der Pol JG, Baumann P, Holzgreve W, Karkut G et al (1992) Genetic amniocentesis in twin pregnancies: results of a multicenter study of 529 cases. Ultrasound Obstet Gynecol 2(1):6–10. doi:10.1046/j.1469-0705.1992.02010006.x
Tongprasert F, Tongsong T, Wanapirak C, Sirirchotiyakul S, Piyamongkol W (2007) Cordocentesis in multifetal pregnancies. Prenat Diagn 27:1100–1103. doi:10.1002/pd.1836
Tongsong T, Wanapirak C, Sirivatanapa P, Piyamongkol W, Sirichotiyakul S, Yampochai A (1998) Amniocentesis-related fetal loss: a cohort study. Obstet Gynecol 92(1):64–67. doi:10.1016/S0029-7844(98)00125-2
Conflict of interest statement
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Supadilokluck, S., Tongprasert, F., Tongsong, T. et al. Amniocentesis in twin pregnancies. Arch Gynecol Obstet 280, 207–209 (2009). https://doi.org/10.1007/s00404-008-0894-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00404-008-0894-y