Archives of Gynecology and Obstetrics

, Volume 280, Issue 2, pp 183–186

Inhibin A levels and severity of preeclampsia

  • Vorapong Phupong
  • Krissada Paiwattananupant
  • Sittisak Honsawek
Original Article

DOI: 10.1007/s00404-008-0886-y

Cite this article as:
Phupong, V., Paiwattananupant, K. & Honsawek, S. Arch Gynecol Obstet (2009) 280: 183. doi:10.1007/s00404-008-0886-y

Abstract

Objective

To evaluate the use of third trimester inhibin A levels to assess the severity of preeclampsia.

Materials and methods

Blood samples were taken from women diagnosed with mild and severe preeclampsia during the third trimester of pregnancy. Blood samples were collected in plain tubes, centrifuged and stored at −80°C until analyzed. All serum samples were measured for inhibin A levels by enzyme-linked immunosorbent assays.

Results

Inhibin A levels were greater in the severe (1,435.9 ± 603.2 pg/mL) than in the mild preeclampsia group (1,021.9 ± 438.8 pg/mL, P = 0.014).

Conclusion

Inhibin A levels rise with increasing severity of disease. However, there is considerable overlap of serum inhibin A levels in women with mild and severe preeclampsia. Inhibin A is therefore not a useful adjunct for the classification of preeclampsia.

Keywords

Inhibin A Preeclampsia Pregnancy Severity 

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Vorapong Phupong
    • 1
  • Krissada Paiwattananupant
    • 1
  • Sittisak Honsawek
    • 2
  1. 1.Department of Obstetrics and Gynecology, Faculty of MedicineChulalongkorn UniversityBangkokThailand
  2. 2.Department of Biochemistry, Faculty of MedicineChulalongkorn UniversityBangkokThailand

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