Skip to main content

Advertisement

Log in

Peritoneal disseminated recurrence and lung metastasis after surgery for stage IA uterine papillary serous carcinoma of the endometrium: a case report

  • Case Report
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Case report

We describe a case of synchronous peritoneal dissemination and multiple lung metastases after surgery for stage IA primary uterine papillary serous carcinoma (UPSC) of the endometrium, revealed by an uncontrollable retention of ascites.

Results and discussion

She was initially treated with a hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy after initial presentation. Tumor recurrence, diagnosed 12 months later, has been treated with six cycles of Paclitaxel 175 mg/m2 and Carboplatin [area under the curve 5 (Calvert Formula)] every 3 weeks and showed an advantage of this regimen. Early recurrences of the stage IA UPSC can occur and continued close surveillance is recommended. We report herein the case about this entity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Alobaid A, Bruchim I, Verkooijen H, Gauthier P, Petignat P (2006) Adjuvant therapy for patients with stage I papillary serous endometrial cancer. Eur J Surg Oncol 32:358–362

    Article  PubMed  CAS  Google Scholar 

  2. Bozas GT, Bamias A, Kastritis E, Rodolakis A, Vlahos G, Papadimitriou CA, Markaki S, Dimopoulos MA (2005) Adjuvant chemotherapy with paclitaxel and carboplatin in non-endometrioid carcinoma of the uterus. Eur J Gynaecol Oncol 26:627–631

    PubMed  CAS  Google Scholar 

  3. Chambers JT, Merino M, Kohorn EI (1987) Uterine papillary serous carcinoma. Obstet Gynecol 69:109–113

    PubMed  CAS  Google Scholar 

  4. Chan JK, Loizzi V, Youssef M, Osann K, Rutgers J, Vasilev SA, Berman ML (2003) Significance of comprehensive surgical staging in noninvasive papillary serous carcinoma of the endometrium. Gynecol Oncol 90:181–185

    Article  PubMed  Google Scholar 

  5. Dietrich CS 3rd, Modesitt SC, DePriest PD, Ueland FR, Wilder J, Reedy MB, Pavlik EJ, Kryscio R, Cibull M, Giesler J, Manahan K, Huh W, Cohn D, Powell M, Slomovitz B, Higgins RV, Merritt W, Hunter J, Puls L, Gehrig P, van Nagell JR Jr (2005) The efficacy of adjuvant platinum-based chemotherapy in Stage I uterine papillary serous carcinoma (UPSC). Gynecol Oncol 99:557–563

    Article  PubMed  CAS  Google Scholar 

  6. Gitsch G, Friedlander ML, Wain GV (1995) Uterine papillary serous carcinoma. A clinical study. Cancer 75:2239–2243

    Article  PubMed  CAS  Google Scholar 

  7. Guzin K, Tekcan C, Naki MM, Kayatas S, Zemheri E, Kanadikirik F, Berkman S (2006) Synchronous primary cancers of the endometrium and ovary: a case report. Eur J Gynaecol Oncol 27:425–428

    PubMed  CAS  Google Scholar 

  8. Hamilton CA, Liou WS, Osann K, Berman ML, Husain A, Teng NN, Kapp DS, Chan JK (2005) Impact of adjuvant therapy on survival of patients with early-stage uterine papillary serous carcinoma. Int J Radiat Oncol Biol Phys 63:839–844

    PubMed  Google Scholar 

  9. Hendrickson M, Ross J, Eifel P (1982) Uterine papillary serous carcinoma. A highly malignant form of endometrial adenocarcinoma. Am J Surg Pathol 6:93–108

    Article  PubMed  CAS  Google Scholar 

  10. Huh WK, Powell M, Leath III CA (2003) Uterine papillary serous carcinoma. Comparisons of outcomes in surgical stage I patients with and without adjuvant therapy. Gynecol Oncol 91:470–475

    Article  PubMed  Google Scholar 

  11. Jeffrey JF, Krepart GV, Lotocki RJ (1986) Papillary serous adenocarcinoma of the endometrium. Obstet Gynecol 67:670–674

    Article  PubMed  CAS  Google Scholar 

  12. Jordan LB, Abdul-Kader M, Al-Nafussi A (2001) Uterine serous papillary carcinoma: histopathologic changes within the female genital tract. Int J Gynecol Cancer 11:283–289

    Article  PubMed  CAS  Google Scholar 

  13. Lim P, Al Kushi A, Gilks B (2001) Early stage uterine papillary serous carcinoma of the endometrium Effect of adjuvant whole abdominal radiotherapy and pathologic parameters on outcome. Cancer 91:752–757

    Article  PubMed  CAS  Google Scholar 

  14. Mallipeddi P, Kapp DS, Teng NN (1993) Long-term survival with adjuvant whole abdominopelvic irradiation for uterine papillary serous carcinoma. Cancer 71:3076–3381

    Article  PubMed  CAS  Google Scholar 

  15. Nguyen NP, Sallah S, Karlsson U, Vos P, Ludin A, Semer D, Tait D, Salehpour M, Jendrasiak G, Robiou C (2001) Prognosis for papillary serous carcinoma of the endometrium after surgical staging. Int J Gynecol Cancer 11:305–311

    Article  PubMed  CAS  Google Scholar 

  16. Rosenberg P, Boeryd B, Simonsen E (1993) A new aggressive treatment approach to high-grade endometrial cancer of possible benefit to patients with stage I uterine papillary cancer. Gynecol Oncol l48:32–37

    Article  Google Scholar 

  17. Slomovitz BM, Burke TW, Eifel PJ (2003) Uterine papillary serous carcinoma (UPSC). A single institution review of 129 cases. Gynecol Oncol 91:463–469

    Article  PubMed  Google Scholar 

  18. Smith RS, Kapp DS, Chen Q (2000) Treatment of high-risk uterine cancer with whole abdominopelvic radiation therapy. Int J Radiat Oncol Biol Phys 48:767–778

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hiroshi Kobayashi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kanayama, S., Yamada, Y., Haruta, S. et al. Peritoneal disseminated recurrence and lung metastasis after surgery for stage IA uterine papillary serous carcinoma of the endometrium: a case report. Arch Gynecol Obstet 278, 277–280 (2008). https://doi.org/10.1007/s00404-007-0550-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-007-0550-y

Keywords

Navigation