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Acupressure and vitamin B6 to relieve nausea and vomiting in pregnancy: a randomized study

Abstract

Objective

To compare the effectiveness of acupressure and vitamin B6 in the outpatient treatment of nausea and vomiting in early pregnancy.

Study design

Pregnant volunteers with symptoms of mild to moderate nausea and vomiting between 6 and 12 weeks’ gestation participated in a 7-day clinical trial. Participants were randomly assigned to receive a device for acupressure therapy and placebo drug or an otherwise identical but non-stimulating placebo device and vitamin B6. The primary outcome measure was self-recorded symptoms according to Rhodes index. Secondary outcome measures were weight gain and medication use.

Results

The mean change in Rhodes index was not significantly different between the two groups. There were no statistically significant differences in weight gain and medication use between the two groups.

Conclusion

Acupressure therapy is not more effective than vitamin B6 in reducing nausea and vomiting in symptomatic women in the first trimester of pregnancy.

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References

  1. Bayrether J, Lewith GT, Pickering R (1994) A double-blind cross over study to evaluate the effectiveness of acupressure at pericardium 6 (P6) in the treatment of early morning sickness (EMS). Complement Ther Med 2:70–76

    Article  Google Scholar 

  2. Berkovitch M, Briggs GG, Chin RKH, von Dadelszen P, Deuchar N, Gadsby R et al (2000) International consensus on standards for studying the efficacy of pharmacological therapies for nausea and vomiting of pregnancy. In: Koren G, Bishai R (eds) Nausea and vomiting of pregnancy: state of the art 2000. Motherisk, Toronto

    Google Scholar 

  3. de Aloysio D, Penacchioni P (1992) Morning sickness control in early pregnancy by Neiguan point acupressure. Obstet Gynecol 80:852–854

    PubMed  Google Scholar 

  4. Deuchar N (1995) Nausea and vomiting in pregnancy: a review of the problem with particular regard to psychological and social aspects. Br J Obstet Gynaecol 102:6–8

    PubMed  CAS  Google Scholar 

  5. Dundee JW, Ghaly RG, Fitzpatrick KT, Lynch GA, Abram WP (1987) Acupuncture to prevent cisplatin-associated vomiting. Lancet 1:1083

    PubMed  Article  CAS  Google Scholar 

  6. Gadsby R, Barnie-Adshead AM, Jagger C (1993) A prospective study of nausea and vomiting during pregnancy. Br J Gen Pract 43:245–248

    PubMed  CAS  Google Scholar 

  7. Heazell A, Thorneycroft J, Walton V, Etherington I (2006) Acupressure for the in-patient treatment of nausea and vomiting in early pregnancy: a randomized control trial. Am J Obstet Gynecol 194:815–820

    PubMed  Article  Google Scholar 

  8. Jewell D, Young G (2002) Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 1:CD000145

    PubMed  Google Scholar 

  9. Lacroix R, Eason E, Melzack R (2000) Nausea and vomiting during pregnancy: A prospective study of its frequency, intensity, and patterns of change. Am J Obstet Gynecol 182:931–937

    PubMed  Article  CAS  Google Scholar 

  10. Mazzotta P, Magee LA (2000) A risk-benefit assessment of pharmacological and nonpharmacological treatments for nausea and vomiting of pregnancy. Drugs 59:781–800

    PubMed  Article  CAS  Google Scholar 

  11. O’Brien B, Zhou Q (1995) Variables related to nausea and vomiting during pregnancy. Birth 22:93–100

    PubMed  Article  CAS  Google Scholar 

  12. Rhodes VA, Watson PM, Johnson MH (1984) Development of reliable and valid measures of nausea and vomiting. Cancer Nurs 7:33–41

    PubMed  Article  CAS  Google Scholar 

  13. Sahakian V, Rouse D, Sipes S, Rose N, Niebyl J (1991) Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstet Gynecol 78:33–36

    PubMed  CAS  Google Scholar 

  14. Vutyavanich T, Wongtra-ngan S, Ruangsri R (1995) Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol 173:881–884

    PubMed  Article  CAS  Google Scholar 

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Correspondence to Vorapong Phupong.

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Jamigorn, M., Phupong, V. Acupressure and vitamin B6 to relieve nausea and vomiting in pregnancy: a randomized study. Arch Gynecol Obstet 276, 245–249 (2007). https://doi.org/10.1007/s00404-007-0336-2

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  • DOI: https://doi.org/10.1007/s00404-007-0336-2

Keywords

  • Acupressure
  • P6 or Neiguan point
  • Vitamin B6
  • Wristband
  • Rhodes index