Abstract
Background
Gestational trophoblastic disease (GTD) after fertility therapy seems to be a rare complication despite the widespread use of these treatments. Despite embryos derived from normally fertilized oocytes were transferred, molar pregnancies still occurring.
Cases
Two patients underwent first cycle of in vitro fertilization (IVF) for management of infertility related to tubal obstruction. GTD was diagnosed by histopathology.
Conclusion
It is unlikely that this complication is directly related to the technique of IVF itself but rather the characteristics of women and the partner attending for assisted conception make them more at risk of molar pregnancies. The management includes prompt curettage and regular follow-up.
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Huang, X., Wang, H., Zhao, X. et al. Gestational trophoblastic disease following in vitro fertilization. Arch Gynecol Obstet 275, 291–293 (2007). https://doi.org/10.1007/s00404-006-0230-3
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DOI: https://doi.org/10.1007/s00404-006-0230-3