Abstract
Background
Pheochromocytoma is a rare disease of the chromaffin cells that secrete catecholamines. It may occur during pregnancy. Bilateral pheochromocytoma in pregnancy is even rarer.
Case
A 26-year-old woman, gravida 2, para 0-0-1-0, 18 weeks’ pregnancy, was initially seen with elevated blood pressure (170/100 mmHg) and mild headache. The cause of hypertension was conventionally investigated and bilateral pheochromocytoma was finally searched for and found. Bilateral adrenalectomy was undertaken at 23 weeks’ gestation and Cesarean section was performed at 31 weeks’ gestation due to intrauterine growth retardation (IUGR) and compromised fetal well-being. The maternal outcome was uneventful and the baby was physiologically complicated only by neonatal jaundice.
Conclusion
Pheochromocytoma should be searched for in the conventionally differential diagnosis in hypertension during pregnancy, especially in the young. Early diagnosis and proper management with medical treatment followed by surgical removal of the tumor usually result in good maternal and fetal outcomes.
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References
Ahlawat SK, Jain S, Kumari S, Varma S, Sharma BK (1999) Pheochromocytoma associated with pregnancy: case report and review of the literature. Obstet Gynecol Surv 54:728–737
Almog B, Kupferminc MJ, Many A, Lessing JB (2000) Pheochromocytoma in pregnancy—a case report and review of the literature. Acta Obstet Gynecol Scand 79:709–711
Chatterjee TK, Parekh U (1985) Phaeochromocytoma in pregnancy. Aust NZ J Obstet Gynaecol 25:290–291
Cunningham FG, Gant NF, Leveno KJ, Gilstrap LCI, Hauth JC, Wenstrom KD (2001) Williams obstetrics, 21st edn. McGraw-Hill, New York
Greenberg M, Moawad AH, Wieties BM, Goldberg LI, Kaplan EI, Greenberg B, Lindheimer MD (1986) Extraadrenal pheochromocytoma: detection during pregnancy using MR imaging. Radiology 161:475–476
Harper MA, Murnaghan GA, Kennedy L, Hadden DR, Atkinson AB (1989) Phaeochromocytoma in pregnancy. Five cases and a review of the literature. Br J Obstet Gynaecol 96:594–606
Lowy C (1980) Endocrine emergencies in pregnancy. Clin Endocrinol Metab 9:569–581
Mastrogiannis DS, Whiteman VE, Mamopoulos M, Salameh WA (1994) Acute endocrinopathies during pregnancy. Clin Obstet Gynecol 37:78–92
Oliver MD, Brownjohn AM, Vinall PS (1990) Medical management of phaeochromocytoma in pregnancy. Aust NZ J Obstet Gynaecol 30:268–271
Samaan NA, Hickey RC, Shutts PE (1988) Diagnosis, localization, and management of pheochromocytoma. Pitfalls and follow-up in 41 patients. Cancer 62:2451–2460
Schenker JG, Granat M (1982) Phaeochromocytoma and pregnancy—an updated appraisal. Aust NZ J Obstet Gynaecol 22:1–10
Van der Vaart CH, Heringa MP, Dullaart RP, Aarnoudse JG (1993) Multiple endocrine neoplasia presenting as phaeochromocytoma during pregnancy. Br J Obstet Gynaecol 100:1144–1145
Venuto R, Burstein P, Schneider R (1984) Pheochromocytoma: antepartum diagnosis and management with tumor resection in the puerperium. Am J Obstet Gynecol 150:431–432
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Phupong, V., Witoonpanich, P., Snabboon, T. et al. Bilateral pheochromocytoma during pregnancy. Arch Gynecol Obstet 271, 277–280 (2005). https://doi.org/10.1007/s00404-004-0654-6
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DOI: https://doi.org/10.1007/s00404-004-0654-6