Antepartum management and neonatal outcome of triplet pregnancies

Abstract

Materials and methods

The maternal and neonatal outcome of 27 triplet and 1 quadruplet gestations was studied at the University Hospital of Verona.

Results

Mean maternal age was 31.7±3.7 years; 24 women (85.7%) were nulliparous. Six (21.4%) patients had conceived spontaneously. Common maternal complications were: preterm labor (78.6%), anemia (57.1%), preeclampsia (25.0%). Thirteen patients (46.4%) had cervical cerclage, 21(75%) received tocolysis, 20 (71.4%) corticosteroid prophylaxis, 4 (14.3%) unfractionated heparin. All patients underwent Caesarean section with mean gestational age of 32±2.5 weeks and mean postoperative stay was 9 days. Three patients were treated in ICU after delivery, 1 was hysterectomized and 6 received blood transfusions. The live newborns were 80, the stillborns 5. Mean birth weight was 1,520±516 g (range 650–2,665), 95.0% being LBW. The following neonatal complications were observed: RDS (28.7%), cerebral hemorrhage (26.2% of II° and 1.2% of III°), anemia (20%), PDA (12.5%), ROP (6.5%), polyglobulia (3.75%), NEC (2.5%). Mean hospitalization time was 30.6 days (range 2–132).

Discussion

Iatrogenic multiple births are increasing as the use of assisted conception techniques expands. Gynecologists should be aware of maternal complications and neonatal outcome of triplet pregnancies and infertility management strategies should try to avoid iatrogenic multiple gestations.

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Correspondence to Giovanni Zanconato.

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Zanconato, G., Poggi, S., Ruffo, R. et al. Antepartum management and neonatal outcome of triplet pregnancies. Arch Gynecol Obstet 271, 320–324 (2005). https://doi.org/10.1007/s00404-004-0632-z

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Keywords

  • Triplets
  • Perinatal care
  • Neonatal outcome