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Anaplastic (pleomorphic) subtype embryonal rhabdomyosarcoma of the cervix

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Abstract

Introduction

Embryonal rhabdomyosarcoma (RMS) of the female genital tract usually occurs in the vagina during childhood. In rare cases, RMS can originate in the uterine cervix, with an incidence peak in the second decade. Recent studies have suggested that it is possible to limit surgery to local excision in stage I cases.

Case report

We present the case of a 13-year-old girl diagnosed with an anaplastic (pleomorphic) subtype embryonal RMS of the endocervix, who was treated successfully with polypectomy followed by ifosfamide-vincristine-actinomycin combination chemotherapy and brachytherapy. The patient exhibits no evidence of recurrence and has normal menstrual function 36 months following initial diagnosis.

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Author information

Authors and Affiliations

  1. Dipartimento di Patologia Umana, Policlinico Universitario, Messina, Italy

    R. A. Caruso & D. Villari

  2. Servizio di Anatomia Patologica dell'Azienda Ospedale Piemonte, Messina, Italy

    P. Napoli & M. Starrantino

Authors
  1. R. A. Caruso
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  2. P. Napoli
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  3. D. Villari
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  4. M. Starrantino
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Corresponding author

Correspondence to R. A. Caruso.

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Caruso, R.A., Napoli, P., Villari, D. et al. Anaplastic (pleomorphic) subtype embryonal rhabdomyosarcoma of the cervix. Arch Gynecol Obstet 270, 278–280 (2004). https://doi.org/10.1007/s00404-003-0504-y

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  • DOI: https://doi.org/10.1007/s00404-003-0504-y

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