Skip to main content

Advertisement

SpringerLink
Log in

Optimizing intralesional triamcinolone acetonide treatment for isolated nail psoriasis: a pilot, intra-subject randomized controlled trial

  • RESEARCH LETTER
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Data availability

No datasets were generated or analysed during the current study.

Abbreviations

ILTAC:

Intralesional triamcinolone acetonide

NP:

Nail psoriasis

NAPSI:

Nail Psoriasis Severity Index

NAPSIm:

Nail Psoriasis Severity Index matrix

NAPSIb:

Nail Psoriasis Severity Index bed

AE:

Adverse event

References

  1. Rigopoulos D, Baran R, Chiheb S et al (2019) Recommendations for the definition, evaluation, and treatment of nail psoriasis in adult patients with no or mild skin psoriasis: a dermatologist and nail expert group consensus. J Am Acad Dermatol 81(1):228–240. https://doi.org/10.1016/j.jaad.2019.01.072

    Article  PubMed  Google Scholar 

  2. Boontaveeyuwat E, Silpa-Archa N, Danchaivijitr N, Wongpraparut C (2019) A randomized comparison of efficacy and safety of intralesional triamcinolone injection and clobetasol propionate ointment for psoriatic nails. J Dermatolog Treat 30(2):117–122. https://doi.org/10.1080/09546634.2018.1476647

    Article  CAS  PubMed  Google Scholar 

  3. Abdelmeniem IM, El Eryan IM, Nofal A, Fouda I, Omar SS (2022) Topical calcipotriol combined with urea 20% versus intralesional injection of triamcinolone acetonide, 5-fluorouracil, and methotrexate in the treatment of nail psoriasis: a comparative study. Dermatol Ther 35(9):e15660. https://doi.org/10.1111/dth.15660

    Article  CAS  PubMed  Google Scholar 

  4. Kenalog-10 Injection (triamcinolone acetonide injection suspension, USP) [package insert]. Princeton, NJ: Bristol-Myers Squibb Company.; [accessed 2023 July 28]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/012041s036,014901s037lbl.pdf

  5. Nantel-Battista M, Richer V, Marcil I, Benohanian A (2014) Treatment of nail psoriasis with intralesional triamcinolone acetonide using a needle-free jet injector: a prospective trial. J Cutan Med Surg 18(1):38–42. https://doi.org/10.2310/7750.2013.13078

    Article  PubMed  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Department of Dermatology, Weill Cornell Medicine, New York, NY, United States

    Jose W. Ricardo & Shari R. Lipner

  2. Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States

    Yuqing Qiu

Authors
  1. Jose W. Ricardo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yuqing Qiu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shari R. Lipner
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

JWR: Methodology, Data collection, Data curation, Validation, Writing-Original draft preparation, Writing-Review and Editing; YQ: Data curation, Statistical analysis, Writing-Editing; SRL: Conceptualization, Methodology, Data collection, Validation, Writing-Original draft preparation, Writing-Review and Editing, Supervision.

Corresponding author

Correspondence to Shari R. Lipner.

Ethics declarations

Ethics approval

The study was conducted according to the guidelines of the Declaration of Helsinki, approved by the Institutional Review Board of Weill Cornell Medicine (record #: 1609017586, approval date 01/08/2021), and registered on ClinicalTrials.gov (NCT03991936). This work is not under consideration at any other journal and has not been previously presented.

Consent to participante

A written informed consent was obtained from all participants included in this study.

Consent for publication

All subjects gave consent for the publication of recognizable patient photographs or other identifiable material with the understanding that this information may be publicly available.

Conflicts of interest

Dr. Jose W. Ricardo and Ms. Yuqing Qiu have no conflicts of interest relevant to the content of the submission. Dr. Lipner has served as a consultant for Ortho-Dermatologics, Moberg Pharmaceuticals, and BelleTorus Corporation.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ricardo, J.W., Qiu, Y. & Lipner, S.R. Optimizing intralesional triamcinolone acetonide treatment for isolated nail psoriasis: a pilot, intra-subject randomized controlled trial. Arch Dermatol Res 316, 113 (2024). https://doi.org/10.1007/s00403-024-02849-w

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00403-024-02849-w

Keywords

Search

Navigation