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Pediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: a national analysis of 2016 Kids’ Inpatient Database

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Abstract

Pediatric-specific studies on Stevens–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are lacking. The objective of this study was to characterize demographics, comorbidities, and outcomes of pediatric SJS and TEN patients on a national level. On average, pediatric SJS/TEN patients were hospitalized longer and had higher mortality rates compared to reports in most previous studies. Better access to dermatologic and multidisciplinary care may help improve pediatric outcomes, although these findings must be corroborated in future studies on larger pediatric populations with SJS and TEN.

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References

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Acknowledgements

This study was not funded.

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Authors and Affiliations

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Contributions

All authors contributed substantially to the production of this manuscript. Study concept and design: SRL. Acquisition of data: ADD. Analysis and interpretation of data: JMF, ADD, SRL. Drafting of the manuscript: JMF, ADD. Critical revision of the manuscript for important intellectual content: SRL. Study supervision: SRL.

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Correspondence to Shari R. Lipner.

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Conflict of interest

Ms. Falotico and Mr. Desai have no conflicts of interest. Dr. Lipner has served as a consultant for Ortho Dermatologics, Hoth Therapeutics, and BelleTorus Corporation.

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Falotico, J.M., Desai, A.D. & Lipner, S.R. Pediatric Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: a national analysis of 2016 Kids’ Inpatient Database. Arch Dermatol Res 315, 653–656 (2023). https://doi.org/10.1007/s00403-022-02414-3

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  • DOI: https://doi.org/10.1007/s00403-022-02414-3

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