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The utility of PROMIS domain measures in dermatologic care

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Abstract

Patient-reported outcome (PRO) measures play an important role in clinical care. Currently, a broad-spectrum, validated PRO measure suitable for all dermatology patients, as part of clinical care, does not exist. Patient-reported Outcome Measures Information System (PROMIS) measures track specific domain outcomes across all diseases. To assess the relevance and utility of a computer-adaptive health assessment consisting of three PROMIS domains in routine dermatologic care. This retrospective study evaluated a PROMIS health assessment, consisting of three computer-adaptive test domains (pain interference, anxiety, and depression), administered as part of routine clinical care in three dermatology clinics at an academic medical center. The primary objective was to identify clinically significant associations between high PROMIS domain scores (i.e., t score > 55) and dermatologic disease, as well as change in PROMIS domain scores in response to treatment. The majority of patients who initiated the assessment completed all domains (88.7%). In patients with atopic dermatitis, acne, hidradenitis suppurativa, and psoriasis, high PROMIS scores correlated with clinically relevant outcomes, such as severe disease, unsuccessful treatment, uncontrolled disease, and the presence of a mental health condition. PROMIS Pain Interference, anxiety and depression identified patients with severe disease, unsuccessful treatment regimens, poorly-controlled disease, and/or mental health comorbidities for multiple skin conditions. Further utilization of PROMIS domains in routine clinical care will promote patient-centered care and improve quality of care.

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Data availability

Dr. Ryan Wolf has full control of the primary data and agrees to allow the journal to review these data if requested.

References

  1. AIR (2011) PROMIS: Dynamic tools to measure health outcomes from the patient perspective. NIH. www.nihpromis.org. Accessed Nov 2019

  2. Alpsoy E, Polat M, FettahlioGlu-Karaman B, Karadag AS, Kartal-Durmazlar P, YalCin B, Emre S, Didar-Balci D, Bilgic-Temel A, Arca E, Koca R, Gunduz K, Borlu M, Ergun T, Dogruk-Kacar S, Cordan-Yazici A, Dursun P, Bilgi CO, Gunes-Bilgili S, Sendur N, Baysal O, Halil-Yavuz I, Yagcioglu G, Yilmaz E, Kavuzlu U, Senol Y (2017) Internalized stigma in psoriasis: a multicenter study. J Dermatol 44:885–891. https://doi.org/10.1111/1346-8138.13841

    Article  PubMed  Google Scholar 

  3. Amtmann D, Kim J, Chung H, Askew RL, Park R, Cook KF (2016) Minimally important differences for Patient Reported Outcomes Measurement Information System pain interference for individuals with back pain. J Pain Res 9:251–255. https://doi.org/10.2147/JPR.S93391

    Article  PubMed  PubMed Central  Google Scholar 

  4. Bernstein DN, Fear K, Mesfin A, Hammert WC, Mitten DJ, Rubery PT, Baumhauer JF (2019) Patient-reported outcomes use during orthopaedic surgery clinic visits improves the patient experience. Musculoskelet Care 17:120–125. https://doi.org/10.1002/msc.1379

    Article  Google Scholar 

  5. Chren MM (2012) The Skindex instruments to measure the effects of skin disease on quality of life. Dermatol Clin 30:231–236. https://doi.org/10.1016/j.det.2011.11.003

    Article  CAS  PubMed  Google Scholar 

  6. Cook KF, Jensen SE, Schalet BD, Beaumont JL, Amtmann D, Czajkowski S, Dewalt DA, Fries JF, Pilkonis PA, Reeve BB, Stone AA, Weinfurt KP, Cella D (2016) PROMIS measures of pain, fatigue, negative affect, physical function, and social function demonstrated clinical validity across a range of chronic conditions. J Clin Epidemiol 73:89–102. https://doi.org/10.1016/j.jclinepi.2015.08.038

    Article  PubMed  PubMed Central  Google Scholar 

  7. Desai NS, Poindexter GB, Monthrope YM, Bendeck SE, Swerlick RA, Chen SC (2008) A pilot quality-of-life instrument for pruritus. J Am Acad Dermatol 59:234–244. https://doi.org/10.1016/j.jaad.2008.04.006

    Article  PubMed  Google Scholar 

  8. Drucker AM, Wang AR, Li WQ, Sevetson E, Block JK, Qureshi AA (2017) The burden of atopic dermatitis: summary of a report for the national eczema association. J Invest Dermatol 137:26–30. https://doi.org/10.1016/j.jid.2016.07.012

    Article  CAS  PubMed  Google Scholar 

  9. HealthMeasures: transforming how health is measured (2018) Northwestern University. www.healthmeasures.net. Accessed Nov 2019

  10. Hitchon CA, Zhang L, Peschken CA, Lix LM, Graff LA, Fisk JD, Patten SB, Bolton J, Sareen J, El-Gabalawy R, Marriott J, Bernstein CN, Marrie R (2019) The validity and reliability of screening measures for depression and anxiety disorders in rheumatoid arthritis. Arthritis Care Res (Hoboken). https://doi.org/10.1002/acr.24011

    Article  Google Scholar 

  11. Ho B, Houck JR, Flemister AS, Ketz J, Oh I, DiGiovanni BF, Baumhauer JF (2016) Preoperative PROMIS scores predict postoperative success in foot and ankle patients. Foot Ankle Int 37:911–918. https://doi.org/10.1177/1071100716665113

    Article  PubMed  Google Scholar 

  12. Kitchen H, Cordingley L, Young H, Griffiths CE, Bundy C (2015) Patient-reported outcome measures in psoriasis: the good, the bad and the missing! Br J Dermatol 172:1210–1221. https://doi.org/10.1111/bjd.13691

    Article  CAS  PubMed  Google Scholar 

  13. Maatoug R, Gorwood P (2019) The psychometrics of the Hospital Anxiety and Depression Scale supports a shorter -12 item- version. Psychiatry Res 274:372–376. https://doi.org/10.1016/j.psychres.2019.02.074

    Article  PubMed  Google Scholar 

  14. Mitchell AJ (2012) Clinical utility of screening for clinical depression and bipolar disorder. Curr Opin Psychiatry 25:24–31. https://doi.org/10.1097/YCO.0b013e32834de45b

    Article  PubMed  Google Scholar 

  15. Oh SH, Bae BG, Park CO, Noh JY, Park IH, Wu WH, Lee KH (2010) Association of stress with symptoms of atopic dermatitis. Acta dermato-venereologica 90:582–588. https://doi.org/10.2340/00015555-0933

    Article  PubMed  Google Scholar 

  16. Parkhouse AR (2019) Experiences of stigma-stress among people living with psoriasis in the United States. Am J Health Behav 43:243–257. https://doi.org/10.5993/AJHB.43.2.2

    Article  PubMed  Google Scholar 

  17. Pavon Blanco A, Turner MA, Petrof G, Weinman J (2019) To what extent do disease severity and illness perceptions explain depression, anxiety and quality of life in hidradenitis suppurativa? Br J Dermatol 180:338–345. https://doi.org/10.1111/bjd.17123

    Article  CAS  PubMed  Google Scholar 

  18. Prisnie JC, Sajobi TT, Wang M, Patten SB, Fiest KM, Bulloch AGM, Pringsheim T, Wiebe S, Jette N (2018) Effects of depression and anxiety on quality of life in five common neurological disorders. Gen Hosp Psychiatry 52:58–63. https://doi.org/10.1016/j.genhosppsych.2018.03.009

    Article  PubMed  Google Scholar 

  19. Sahni A, Agius M (2017) The Use of the PHQ9 self-rating scale to assess depression within primary care. Psychiatr Danub 29:615–618

    PubMed  Google Scholar 

  20. Scharloo M, Kaptein AA, Weinman J, Bergman W, Vermeer BJ, Rooijmans HG (2000) Patients' illness perceptions and coping as predictors of functional status in psoriasis: a 1-year follow-up. Br J Dermatol 142:899–907

    Article  CAS  Google Scholar 

  21. Shavit E, Dreiher J, Freud T, Halevy S, Vinker S, Cohen AD (2015) Psychiatric comorbidities in 3207 patients with hidradenitis suppurativa. J Eur Acad Dermatol Venereol JEADV 29:371–376. https://doi.org/10.1111/jdv.12567

    Article  CAS  PubMed  Google Scholar 

  22. Silverberg JI, Gelfand JM, Margolis DJ, Boguniewicz M, Fonacier L, Grayson MH, Ong PY, Chiesa Fuxench ZC, Simpson EL (2019) Measurement properties of the hospital anxiety and depression scale used in atopic dermatitis in adults. J Invest Dermatol 139:1388–1391. https://doi.org/10.1016/j.jid.2018.11.029

    Article  CAS  PubMed  Google Scholar 

  23. Stalder JF, Barbarot S, Wollenberg A, Holm EA, De Raeve L, Seidenari S, Oranje A, Deleuran M, Cambazard F, Svensson A, Simon D, Benfeldt E, Reunala T, Mazereeuv J, Boralevi F, Kunz B, Misery L, Mortz CG, Darsow U, Gelmetti C, Diepgen T, Ring J, Moehrenschlager M, Gieler U, Taieb A, Group P-SI (2011) Patient-Oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe. Allergy 66:1114–1121. https://doi.org/10.1111/j.1398-9995.2011.02577.x

    Article  PubMed  Google Scholar 

  24. Stumpf A, Pfleiderer B, Fritz F, Osada N, Chen SC, Stander S (2018) Assessment of quality of life in chronic pruritus: relationship between ItchyQoL and dermatological life quality index in 1,150 patients. Acta dermato-venereologica 98:142–143. https://doi.org/10.2340/00015555-2782

    Article  PubMed  Google Scholar 

  25. Swerlick RA, Zhang C, Patel A, Chren MM, Chen S (2018) The Skindex-mini: a streamlined QOL measurement tool suitable for routine use in clinic. J Am Acad Dermatol. https://doi.org/10.1016/j.jaad.2018.12.035

    Article  PubMed  Google Scholar 

  26. Tzur Bitan D, Krieger I, Comaneshter D, Cohen AD, Feingold D (2019) The association between the socioeconomic status and anxiety-depression comorbidity in patients with psoriasis: a nationwide population-based study. J Eur Acad Dermatol Venereol JEADV. https://doi.org/10.1111/jdv.15651

    Article  PubMed  Google Scholar 

  27. Witter JP (2016) Introduction: PROMIS a first look across diseases. J Clin Epidemiol 73:87–88. https://doi.org/10.1016/j.jclinepi.2016.02.014

    Article  PubMed  Google Scholar 

  28. Wu JJ, Feldman SR, Koo J, Marangell LB (2018) Epidemiology of mental health comorbidity in psoriasis. J Dermatol Treat 29:487–495. https://doi.org/10.1080/09546634.2017.1395800

    Article  CAS  Google Scholar 

  29. Yaghmaie P, Koudelka CW, Simpson EL (2013) Mental health comorbidity in patients with atopic dermatitis. J Allergy Clin Immunol 131:428–433. https://doi.org/10.1016/j.jaci.2012.10.041

    Article  PubMed  Google Scholar 

  30. Yost KJ, Eton DT, Garcia SF, Cella D (2011) Minimally important differences were estimated for six Patient-Reported Outcomes Measurement Information System-Cancer scales in advanced-stage cancer patients. J Clin Epidemiol 64:507–516. https://doi.org/10.1016/j.jclinepi.2010.11.018

    Article  PubMed  PubMed Central  Google Scholar 

  31. Yu SH, Silverberg JI (2015) Association between atopic dermatitis and depression in US adults. J Invest Dermatol 135:3183–3186. https://doi.org/10.1038/jid.2015.337

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors would like to thank: Kathleen Fear in the UR Health Lab for her technical support, data extraction, and data organization for this project; Claire Porterfield for her technical assistance with chart review data collection and management during her summer medical research rotation; and Zachary Skabelund for his data management assistance during his summer medical research rotation.

Funding

This study was supported by the University of Rochester Department of Dermatology. No funding was received for the conduct of the study or preparation of the manuscript.

Author information

Authors and Affiliations

  1. School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA

    Fatema Esaa

  2. Department of Dermatology, University of Rochester Medical Center, 601 Elmwood Ave, Box 697, Rochester, NY, 14642, USA

    James Prezzano, Alice Pentland & Julie Ryan Wolf

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  1. Fatema Esaa
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  2. James Prezzano
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  3. Alice Pentland
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  4. Julie Ryan Wolf
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Contributions

All authors of this research paper contributed to the study conception and design. All authors have directly participated in the planning, execution, or analysis of the study. Material preparation, data collection and analyses were performed by FE, Dr. JP, and Dr. JRW. The first draft of the manuscript was written by FE and all authors commented on previous versions of the manuscript. All authors of this paper have read and approved the final version submitted. The contents of this manuscript have not been previously published or copyrighted. This manuscript is not under consideration for publication by another journal. The contents of this manuscript will not be submitted or published elsewhere while acceptance by the Journal is under consideration.

Corresponding author

Correspondence to Julie Ryan Wolf.

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All authors have no conflicts of interest to disclose.

Ethics approval

This study was approved by the University of Rochester Research Subject Review Board (RSRB#: 00062591 and 00069111).

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Esaa, F., Prezzano, J., Pentland, A. et al. The utility of PROMIS domain measures in dermatologic care. Arch Dermatol Res 313, 17–24 (2021). https://doi.org/10.1007/s00403-020-02074-1

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  • DOI: https://doi.org/10.1007/s00403-020-02074-1

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