It is well established that Androgenetic Alopecia (AGA) occurs in genetically predisposed individuals but little is known of its non-genetic risk factors. The aim of the study was to investigate the role of the Mediterranean diet in determining the risk of AGA. A hospital-based case-control study was conducted in the outpatient clinics of the hospital “Istituto Dermopatico dell’Immacolata, Rome, Italy”. We included 104 males and 108 controls not affected by AGA. Controls were frequency matched to cases. Information on socio-demographic characteristics, medical history, smoking and diet were collected for all patients. Logistic regression was used to estimate odds ratio and 95% confidence intervals. After controlling for age, education, body mass index and family history of AGA, protective effects for AGA were found for high consumption (≥ 3 times weekly) of raw vegetables (OR 0.43; 95% CI 0.21–0.89) and high consumption of fresh herbs (3 or more regularly) (OR 0.44; 95% CI 0.22–0.87). We suggest that some foods of the Mediterranean diet, say fresh herbs and salad, may reduce the risk of AGA onset.
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We thank Dr. Marcella Ribuffo for helping in the assessment of AGA and for the training of the dermatologist in charge of data collection.
Conflict of interest
The authors declared that they have no conflicts of interest to disclose.
This work was supported by the Italian Ministry of Health (Ricerca Corrente 5.1).
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Fortes, C., Mastroeni, S., Mannooranparampil, T. et al. Mediterranean diet: fresh herbs and fresh vegetables decrease the risk of Androgenetic Alopecia in males. Arch Dermatol Res 310, 71–76 (2018). https://doi.org/10.1007/s00403-017-1799-z
- Androgenetic Alopecia
- Risk factors
- Case control