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Skin barrier and microbiome in acne

Archives of Dermatological Research volume 310, pages 181–185 (2018)Cite this article

Abstract

Acne is an immune-mediated chronic inflammatory disease. Although several factors are involved in its pathophysiology, this process is not completely understood. Androgen hormone activity increases sebum production inside the pilosebaceous follicle, adjusting the environment for the development of Propionibacterium acnes which triggers inflammation. Knowing how others factors such as the skin barrier and microbiome are involved in acne, can help in understanding more about the disease and may help to conduct a better treatment.

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  1. Federal University of São Paulo (Escola Paulista de Medicina—Universidade Federal de São Paulo), Rua Eugenio Bettarello 55 ap 134B, São Paulo, SP, Brazil

    M. A. Rocha & E. Bagatin

Authors
  1. M. A. Rocha
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  2. E. Bagatin
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Correspondence to M. A. Rocha.

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Rocha, M.A., Bagatin, E. Skin barrier and microbiome in acne. Arch Dermatol Res 310, 181–185 (2018). https://doi.org/10.1007/s00403-017-1795-3

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  • DOI: https://doi.org/10.1007/s00403-017-1795-3

Keywords

  • Acne
  • Skin barrier
  • Microbiome
  • Microbiota