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Treatment goals in psoriasis routine care


The treatment goal algorithm for psoriasis, first originated in 2007, has ever since been adopted into treatment guidelines. It remained unclear how many patients have experienced the use of treatment goals in routine care and how these are perceived. The aim of the pilot study was to get first insight in the use and impact of therapeutic goals in a large cohort of patients with psoriasis in routine care. This study is a multicenter, non-interventional, cross-sectional health care study in n = 213 dermatology centers across Germany. A standardized physician and patient questionnaire was used, including demographics, disease and treatment characteristics. To evaluate patient treatment perception and satisfaction, a questionnaire (PsoSat) addressing 8 specific items was designed. Consistency and validity of the questionnaire were controlled by factor analyses and reliability tests. In total n = 1,883 patients were included for analysis (54.2 % male). Mean age was 52 years, mean disease duration 19 years. In total 45.5 % (n = 856) stated an improvement of psoriatic symptoms in the last 4 weeks. In patients including treatment goals, the course of psoriasis in the last 4 weeks was rated significantly better and predicted significantly higher patient satisfaction. Patients reporting periodic outcomes measurement of psoriasis treatment, also had significantly better course of disease, higher satisfaction and a lower psoriasis severity. A majority of patients experienced the use of treatment goals in practice. The association of using treatment goals with clinical outcomes and treatment satisfaction was markedly positive. These findings indicate that the use of treatment goals and outcome measurements in fact improve psoriasis management.

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The study has been supported by a research grant from Biogen Idec GmbH, Ismaning, Germany.

Augustin M, Reich K and Radtke MA have conducted clinical studies, investigations in health services research, consultations or have been invited speakers for Abbvie, Biogen Idec, Janssen, MSD Sharp & Dohme, Pfizer, Merck Serono, Novartis, Medac, Lilly-Pharma and Celegene. Spehr C has no conflicts of interest to declare.

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Correspondence to Matthias Augustin.

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Radtke, M.A., Reich, K., Spehr, C. et al. Treatment goals in psoriasis routine care. Arch Dermatol Res 307, 445–449 (2015).

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  • Psoriasis
  • Treatment
  • Treatment goals
  • Outcomes
  • Quality of care