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Scleroderma - news to tell

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Abstract

Scleroderma is a chronic fibrosing disease, in which an early inflammatory reaction precedes the fibrotic response. Systematic analysis of the pathways involved in the development of the disease together with information derived from novel animal models have helped to better understand the mechanisms that trigger and sustain fibrotic reactions.

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Acknowledgements

Work on scleroderma in the Department of Dermatology is supported by the Bundesministerium für Bildung und Forschung through the German Network for Systemic Scleroderma (01GM0310), Deutsche Forschungsgemeinschaft through KR558 and SFB 589 and Actelion Deutschland (TPL-532-MEN-DE-V01-2005-07). We wish to thank Mrs. Angela Fehr and Barbara Damm for excellent assistance in managing the German Network for Systemic Scleroderma (www.sklerodermie.info).

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Authors and Affiliations

  1. Department of Dermatology, University of Cologne, Kerpener Str. 62, D-50937, Cologne, Germany

    Beate Eckes, Nicolas Hunzelmann, Pia Moinzadeh & Thomas Krieg

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  1. Beate Eckes
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Correspondence to Thomas Krieg.

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Eckes, B., Hunzelmann, N., Moinzadeh, P. et al. Scleroderma - news to tell. Arch Dermatol Res 299, 139–144 (2007). https://doi.org/10.1007/s00403-007-0756-7

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  • DOI: https://doi.org/10.1007/s00403-007-0756-7

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