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Comparison of sebum secretion, skin type, pH in humans with and without acne

  • Myo-Kyoung Kim
  • Sun-Young Choi
  • Hee-Jin Byun
  • Chang-Hun Huh
  • Kyoung-Chan Park
  • Rajul A. Patel
  • Annie H. Shinn
  • Sang-Woong YounEmail author
Original Paper

Abstract

Differences of skin type and pH between subjects with and without acne have not been investigated. In addition, the relationship between sebum secretion and pH in these populations has not been determined. This study assessed the differences in objective and subjective skin types between these two groups. Secondly, this study evaluated the difference in pH on five facial areas (forehead, nose, chin, right and left cheeks) between the two populations. Lastly, the relationship between pH and sebum secretion was analyzed in each population. Sebum casual levels (CL) of the five facial areas in 36 Koreans with acne and 47 Koreans without acne were measured by using a Sebumeter SM 815® and subjects were classified into objective skin types by CL. Subjects reported the type of skin they believed they had, which determined the subjective skin type. The pH levels of the five facial areas were measured by the Skin-pH-Meter PH 905®. Data were assessed with adequate statistical tests depending on data type and distribution. Among the five areas, the nose of the subjects with acne showed a significantly higher CL, compared to the subjects without acne. This difference in CL on the nose resulted in the difference in CL on the T-zone and mean facial sebum excretions (MFSE). Although CL differed, objective skin types did not differ between the two groups (P > 0.05), but the subjective skin types differed significantly (P = 0.001). In addition, the objective skin types were significantly different than the subjective skin types in subjects with acne (P = 0.001), whereas the two skin types did not differ in subjects without acne. Subjects with acne actually overestimated their skin types and stated their skin types were “oilier” than they were. In respect to pH, none of the five areas differed significantly between the two groups. Among the five sites in subjects with acne, CL showed a significant negative correlation with pH on the left (r = 0.12) and right (r = 0.15) cheeks, which resulted in a significant negative correlation on the U-zone (r = 0.14). In contrast, in subjects without acne, there was a significant negative correlation between CL and pH on the forehead (r = 0.10) and chin (r = 0.16), which led to a significant negative correlation on the T-zone (r = 0.14).

Keywords

Acne Skin type pH Sebumeter® Skin-pH-Meter® 

References

  1. 1.
    Greenman J (1981) Follicular pH and the development of acne. Int J Dermatol 20:656–658PubMedCrossRefGoogle Scholar
  2. 2.
    Greenman J, Holland KT, Cunliffe WJ (1983) Effects of pH on biomass, maximum specific growth rate and extracellular enzyme production by three species of cutaneous propionibacteria grown in continuous culture. J Gen Microbiol 129:1301–1307PubMedGoogle Scholar
  3. 3.
    Hachem JP, Crumrine D, Fluhr J, Brown BE, Feingold KR, Elias PM (2003) pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion. J Invest Dermatol 121:345–353PubMedCrossRefGoogle Scholar
  4. 4.
    Harper JC, Thiboutot DM (2003) Pathogenesis of acne: recent research advances. Adv Dermatol 19:1–10PubMedGoogle Scholar
  5. 5.
    Harris HH, Downing DT, Stewart ME, Strauss JS (1983) Sustainable rates of sebum secretion in acne patients and matched normal control subjects. J Am Acad Dermatol 8:200–203PubMedCrossRefGoogle Scholar
  6. 6.
    Holland KT, Greenman J, Cunliffe WJ (1979) Growth of cutaneous propionibacteria on synthetic medium; growth yields and exoenzyme production. J Appl Bacteriol 47:383–394PubMedGoogle Scholar
  7. 7.
    Korting HC, Kerscher M, Schafer-Korting M, Berchtenbreiter U (1993) Influence of topical erythromycin preparations for acne vulgaris on skin surface pH. Clin Investig 71:644–648PubMedCrossRefGoogle Scholar
  8. 8.
    Le Fur I, Lopez S, Morizot F, Guinott C, Tschachler E (1999) Comparison of cheek and forehead regions by bioengineering methods in women with different self-reported cosmetic skin types. Skin Res Technol 5:182–188CrossRefGoogle Scholar
  9. 9.
    Leyden J, Bergfeld W, Drake L, Dunlap F, Goldman MP, Gottlieb AB, Heffernan MP, Hickman JG, Hordinsky M, Jarrett M, Kang S, Lucky A, Peck G, Phillips T, Rapaport M, Roberts J, Savin R, Sawaya ME, Shalita A, Shavin J, Shaw JC, Stein L, Stewart D, Strauss J, Swinehart J, Swinyer L, Thiboutot D, Washenik K, Weinstein G, Whiting D, Pappas F, Sanchez M, Terranella L, Waldstreicher J (2004) A systemic type I 5 alpha-reductase inhibitor is ineffective in the treatment of acne vulgaris. J Am Acad Dermatol 50:443–447PubMedCrossRefGoogle Scholar
  10. 10.
    Lopez S, Le Fur I, Morizot F, Heuvin G, Guinot C, Tschachler E (2000) Transepidermal water loss, temperature and sebum levels on women’s facial skin follow characteristic patterns. Skin Res Technol 6:31–36PubMedCrossRefGoogle Scholar
  11. 11.
    Park SG, Kim YD, Kim JJ, Kang SH (1999) Two possible classifications of facial skin type by two parameters in Korean women: sebum excretion rate (SER) and skin surface relief (SSR). Skin Res Technol 5:189–194CrossRefGoogle Scholar
  12. 12.
    Pierard-Franchimont C, Pierard GE, Saint-Leger D, Leveque JL, Kligman AM (1991) Comparison of the kinetics of sebum secretion in young women with and without acne. Dermatologica 183:120–122PubMedCrossRefGoogle Scholar
  13. 13.
    Pierard GE, Pierard-Franchimont C, Le T (1987) Seborrhoea in acne-prone and acne-free patients. Dermatologica 175:5–9PubMedGoogle Scholar
  14. 14.
    Pierard GE, Pierard-Franchimont C, Marks R, Paye M, Rogiers V (2000) EEMCO guidance for the in vivo assessment of skin greasiness. The EEMCO Group. Skin Pharmacol Appl Skin Physiol 13:372–389PubMedCrossRefGoogle Scholar
  15. 15.
    Wendling PA, Dell’Acqua G (2003) Skin biophysical properties of a population living in Valais, Switzerland. Skin Res Technol 9:331–338PubMedCrossRefGoogle Scholar
  16. 16.
    Youn SW, Kim SJ, Hwang IA, Park KC (2002) Evaluation of facial skin type by sebum secretion: discrepancies between subjective descriptions and sebum secretion. Skin Res Technol 8:168–172PubMedCrossRefGoogle Scholar
  17. 17.
    Youn SW, Na JI, Choi SY, Huh CH, Park KC (2005) Regional and seasonal variations in facial sebum secretions: a proposal for the definition of combination skin type. Skin Res Technol 11:189–195PubMedCrossRefGoogle Scholar
  18. 18.
    Youn SW, Park ES, Lee DH, Huh CH, Park KC (2005) Does facial sebum excretion really affect the development of acne? Br J Dermatol 153:919–924PubMedCrossRefGoogle Scholar
  19. 19.
    Zlotogorski A (1987) Distribution of skin surface pH on the forehead and cheek of adults. Arch Dermatol Res 279:398–401PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Myo-Kyoung Kim
    • 1
  • Sun-Young Choi
    • 2
    • 3
  • Hee-Jin Byun
    • 2
    • 3
  • Chang-Hun Huh
    • 2
    • 3
  • Kyoung-Chan Park
    • 2
    • 3
  • Rajul A. Patel
    • 1
  • Annie H. Shinn
    • 1
  • Sang-Woong Youn
    • 2
    • 3
    Email author
  1. 1.Pharmacy PracticeUniversity of the Pacific, Thomas J. Long School of PharmacyStocktonUSA
  2. 2.Department of DermatologySeoul National University, College of MedicineKyounggiSouth Korea
  3. 3.Department of DermatologySeoul National University Bundang HospitalBundang-Gu, SeongnamSouth Korea

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