Skip to main content

Advertisement

Log in

Bone remodeling and cortical thinning distal to the femoral stem: a retrospective review

  • Hip Arthroplasty
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Introduction

There is a paucity of information on the bone remodeling that occurs distal to the femoral stem following total hip arthroplasty as most previous studies have focused on proximal changes. In this study, we report the cortical thinning that occur distal to the femoral stem after primary total hip arthroplasty.

Methods

A retrospective review was performed at one institution over a 5-year period. 156 primary total hip arthroplasty procedures were included. The Cortical Thickness Index (CTI) was measured on both operative and non-operative hips at 1 cm, 3 cm and 5 cm below the prosthetic stem tip on anteroposterior radiographic images pre-operatively as well as at 6 months, 12 months and 24 months post-operatively. The difference in average CTI was measured using paired t-tests.

Results

There were statistically significant decreases in CTI distal to the femoral stem at 12 months and 24 months (-1.3% and -2.8%, respectively). Greater losses were seen in female patients, patients older than 75, and patients with BMI less than 35 at 6 months postoperative. There were no differences in CTI at any time point on the non-operative side.

Conclusion

The current study demonstrates that patients undergo bone loss as measured by CTI distal to the stem in the first 2 years following total hip arthroplasty. Comparison to the contralateral non-operative side confirms that this change is greater than expected for the natural aging process. A greater understanding of these changes will help optimize post-operative management and direct future innovations in implant design.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Eskelinen A, Remes V, Helenius I, Pulkkinen P, Nevalainen J, Paavolainen P (2005) Total hip arthroplasty for primary osteoarthrosis in younger patients in the Finnish arthroplasty register. 4,661 primary replacements followed for 0–22 years. Acta Orthop 76:28–41. https://doi.org/10.1080/00016470510030292

    Article  PubMed  Google Scholar 

  2. Chen J-H, Liu C, You L, Simmons CA (2010) Boning up on Wolff’s Law: mechanical regulation of the cells that make and maintain bone. J Biomech 43:108–118. https://doi.org/10.1016/j.jbiomech.2009.09.016

    Article  PubMed  Google Scholar 

  3. Cabahug-Zuckerman P, Frikha-Benayed D, Majeska RJ, Tuthill A, Yakar S, Judex S, Schaffler MB (2016) Osteocyte apoptosis caused by hindlimb unloading is required to trigger osteocyte RANKL production and subsequent resorption of cortical and trabecular bone in mice femurs. J bone Miner Res 31:1356–1365. https://doi.org/10.1002/jbmr.2807

    Article  CAS  PubMed  Google Scholar 

  4. Cole EW, Moulton SG, Gobezie R, Romeo AA, Walker JB, Lederman E, Denard PJ (2020) Five-year radiographic evaluation of stress shielding with a press-fit standard length humeral stem. JSES Int 4:109–113. https://doi.org/10.1016/j.jses.2019.11.002

    Article  PubMed  PubMed Central  Google Scholar 

  5. Yan SG, Chevalier Y, Liu F, Hua X, Schreiner A, Jansson V, Schmidutz F (2020) Metaphyseal anchoring short stem hip arthroplasty provides a more physiological load transfer: a comparative finite element analysis study. J Orthop Surg Res 15:498. https://doi.org/10.1186/s13018-020-02027-4

    Article  PubMed  PubMed Central  Google Scholar 

  6. Abdel MP, Houdek MT, Watts CD, Lewallen DG, Berry DJ (2016) Epidemiology of periprosthetic femoral fractures in 5417 revision total hip arthroplasties. Bone Joint J 98:468–474. https://doi.org/10.1302/0301-620X.98B4.37203

    Article  PubMed  Google Scholar 

  7. Pavelka T, Salášek M, Weisová D (2017) Periprosthetic femoral fractures after total hip replacement: our results and treatment complications. Acta Chir Orthop Traumatol Cech 84:52–58

    Article  CAS  PubMed  Google Scholar 

  8. Cho YJ, Chun YS, Rhyu KH, Baek JH, Liang H (2016) Distal femoral cortical hypertrophy after hip arthroplasty using a cementless doubletapered femoral stem. J Orthop Surg 24:317–322. https://doi.org/10.1177/1602400309

    Article  Google Scholar 

  9. Delsmann MM, Strahl A, Mühlenfeld M, Jandl NM, Beil FT, Ries C, Rolvien T (2021) High prevalence and undertreatment of osteoporosis in elderly patients undergoing total hip arthroplasty. Osteoporos Int 32:1661–1668. https://doi.org/10.1007/s00198-021-05881-y

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Cruz E, Natera L, Mitjans M, Antón C, Cañete E, Cases E (2020) Is there a significant decrease in the femoral cortical bone around Furlong(®) stems after 18 years of follow-up? Eur J Orthop Surg Traumatol 30:117–122. https://doi.org/10.1007/s00590-019-02539-8

    Article  PubMed  Google Scholar 

  11. Nguyen BN, Hoshino H, Togawa D, Matsuyama Y (2018) Cortical thickness index of the proximal femur: a radiographic parameter for preliminary assessment of bone mineral density and osteoporosis status in the age 50 years and over population. Clin Orthop Surg 10:149–156. https://doi.org/10.4055/cios.2018.10.2.149

    Article  PubMed  PubMed Central  Google Scholar 

  12. Baumgärtner R, Heeren N, Quast D, Babst R, Brunner A (2015) Is the cortical thickness index a valid parameter to assess bone mineral density in geriatric patients with hip fractures? Arch Orthop Trauma Surg 135:805–810. https://doi.org/10.1007/s00402-015-2202-1

    Article  PubMed  Google Scholar 

  13. Van Rietbergen B, Huiskes R, Weinans H, Sumner DR, Turner TM, Galante JO (1993) ESB research award 1992. the mechanism of bone remodeling and resorption around press-fitted THA stems. J Biomech 26:369–382. https://doi.org/10.1016/0021-9290(93)90001-u

    Article  PubMed  Google Scholar 

  14. Huiskes R (1990) The various stress patterns of press-fit, ingrown, and cemented femoral stems. Clin Orthop Relat Res. 261:27–38

    Article  Google Scholar 

  15. Decking R, Puhl W, Simon U, Claes LE (2006) Changes in strain distribution of loaded proximal femora caused by different types of cementless femoral stems. Clin Biomech 21:495–501. https://doi.org/10.1016/j.clinbiomech.2005.12.011

    Article  Google Scholar 

  16. Ritter MA, Fechtman RW (1988) Distal cortical hypertrophy following total hip arthroplasty. J Arthroplasty 3:117–121. https://doi.org/10.1016/s0883-5403(88)80076-7

    Article  CAS  PubMed  Google Scholar 

  17. Peitgen DS, Innmann MM, Merle C, Gotterbarm T, Moradi B, Streit MR (2018) Periprosthetic bone mineral density around uncemented titanium stems in the second and third decade after total hip arthroplasty: a DXA study after 12, 17 and 21 years. Calcif Tissue Int 103:372–379. https://doi.org/10.1007/s00223-018-0438-9

    Article  CAS  PubMed  Google Scholar 

  18. Knutsen AR, Lau N, Longjohn DB, Ebramzadeh E, Sangiorgio SN (2017) Periprosthetic femoral bone loss in total hip arthroplasty: systematic analysis of the effect of stem design. Hip Int 27:26–34. https://doi.org/10.5301/hipint.5000413

    Article  PubMed  Google Scholar 

  19. Streit MR, Innmann MM, Merle C, Bruckner T, Aldinger PR, Gotterbarm T (2013) Long-term (20- to 25-year) results of an uncemented tapered titanium femoral component and factors affecting survivorship. Clin Orthop Relat Res 471:3262–3269. https://doi.org/10.1007/s11999-013-3033-4

    Article  PubMed  PubMed Central  Google Scholar 

  20. Kanto M, Fukunishi S, Fukui T, Nishio S, Fujihara Y, Okahisa S, Takeda Y, Yoshiya S, Tachibana T (2020) Radiological evaluation of the relationship between cortical hypertrophy and stress shielding after total hip arthroplasty using a cementless stem. Arthroplast Today 6:894–900. https://doi.org/10.1016/j.artd.2020.09.018

    Article  PubMed  PubMed Central  Google Scholar 

  21. Katsimihas M, Katsimihas G, Lee MB, Learmonth ID (2006) Distal femoral cortical hypertrophy: predisposing factors and their effect on clinical outcome. Hip Int 16:18–22. https://doi.org/10.5301/hip.2008.967

    Article  CAS  PubMed  Google Scholar 

  22. Brodt S, Matziolis G, Buckwitz B, Zippelius T, Strube P, Roth A (2020) Long-term follow-up of bone remodelling after cementless hip arthroplasty using different stems. Sci Rep 10:10143. https://doi.org/10.1038/s41598-020-67189-x

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Goto K, Furuya Y, Oda K, Minami R, Sano K, Sugimoto M, Matsuda S (2018) Long-term results of total hip arthroplasty using Charnley Elite-Plus stem and the effect of stem geometry on radiographic distal femoral cortical hypertrophy. J Orthop Sci 23:365–370. https://doi.org/10.1016/j.jos.2017.12.003

    Article  PubMed  Google Scholar 

  24. Iwase T, Morita D, Takemoto G (2020) The effects of patient characteristics and stem alignment on distal femoral cortical hypertrophy after cemented polished tapered stem implantation. Eur J Orthop Surg Traumatol 30:559–567. https://doi.org/10.1007/s00590-019-02605-1

    Article  PubMed  Google Scholar 

  25. Evans AL, Paggiosi MA, Eastell R, Walsh JS (2015) Bone density, microstructure and strength in obese and normal weight men and women in younger and older adulthood. J bone Miner Res 30:920–928. https://doi.org/10.1002/jbmr.2407

    Article  PubMed  Google Scholar 

  26. Prieto-Alhambra D, Premaor MO, FinaAvilés F, Hermosilla E, Martinez-Laguna D, Carbonell-Abella C, Nogués X, Compston JE, Díez-Pérez A (2012) The association between fracture and obesity is site-dependent: a population-based study in postmenopausal women. J bone Miner Res 27:294–300. https://doi.org/10.1002/jbmr.1466

    Article  PubMed  Google Scholar 

  27. Alswat KA (2017) Gender disparities in osteoporosis. J Clin Med Res. 9:382–387. https://doi.org/10.14740/jocmr2970w

    Article  PubMed  PubMed Central  Google Scholar 

  28. Pitto RP, Mueller LA, Reilly K, Schmidt R, Munro J (2007) Quantitative computer-assisted osteodensitometry in total hip arthroplasty. Int Orthop 31:431–438. https://doi.org/10.1007/s00264-006-0257-x

    Article  CAS  PubMed  Google Scholar 

  29. Gausden EB, Beiene ZA, Blevins JL, Christ AB, Chalmers BP, Helfet DL, Sculco PK, Mayman DJ (2021) Periprosthetic femur fractures after total hip arthroplasty: does the mode of failure correlate with classification? J Arthroplasty 36:2597–2602. https://doi.org/10.1016/j.arth.2021.02.048

    Article  PubMed  Google Scholar 

  30. Marsland D, Mears SC (2012) A review of periprosthetic femoral fractures associated with total hip arthroplasty. Geriatr Orthop Surg Rehabil 3:107–120. https://doi.org/10.1177/2151458512462870

    Article  PubMed  PubMed Central  Google Scholar 

  31. Deng J, Wang G, Li J, Wang S, Li M, Yin X, Zhang L, Tang P (2021) A systematic review and meta-analysis comparing arthroplasty and internal fixation in the treatment of elderly displaced femoral neck fractures. OTA Int 4:e087. https://doi.org/10.1097/OI9.0000000000000087

    Article  PubMed  Google Scholar 

  32. Ries C, Boese CK, Dietrich F, Miehlke W, Heisel C (2019) Femoral stem subsidence in cementless total hip arthroplasty: a retrospective single-centre study. Int Orthop 43:307–314. https://doi.org/10.1007/s00264-018-4020-x

    Article  PubMed  Google Scholar 

  33. Campbell D, Mercer G, Nilsson KG, Wells V, Field JR, Callary SA (2011) Early migration characteristics of a hydroxyapatite-coated femoral stem: an RSA study. Int Orthop 35:483–488. https://doi.org/10.1007/s00264-009-0913-z

    Article  PubMed  Google Scholar 

  34. Rattanaprichavej P, Laoruengthana A, Chotanaphuti T, Khuangsirikul S, Phreethanutt C, Pongpirul K (2019) Subsidence of hydroxyapatite-coated femoral stem in dorr type C proximal femoral morphology. J Arthroplasty 34:2011–2015. https://doi.org/10.1016/j.arth.2019.05.017

    Article  PubMed  Google Scholar 

Download references

Funding

No funding was received for this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sameer Naranje.

Ethics declarations

Conflict of interest

The authors have not published, posted, or submitted any other papers from this study. The authors have no disclosures or conflicts of interest.

Ethical approval

Ethical approval was granted by UAB Institutional Review Board for this study.

Informed consent

Informed consent was not required for this study per our institutions IRB.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Messner, M., Jacob, R., Hagewood, J. et al. Bone remodeling and cortical thinning distal to the femoral stem: a retrospective review. Arch Orthop Trauma Surg 143, 6461–6467 (2023). https://doi.org/10.1007/s00402-023-04860-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00402-023-04860-8

Keywords

Navigation